Evaluation of the Role of Genicular Nerve Block When Combined With Adductor Canal Block for Pain Control Following Knee Arthroscopy

NCT06951204 | Completed DMC

• 1 other identifier: FMASU MS170/2024
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The intervention tests the efficacy of Genicular nerve block when combined with Adductor canal block in comparison with Adductor canal block alone to control post operative pain in knee arthroscopy

Conditions

Post Operative Pain Control

Keywords

Genicular nerve block; Adductor canal block; motor sparing analgesia

Outcome Measures

Primary Outcomes (1)

• post-operative pain after 6 hours after the time of administration of the block according to VAS score.

  * To assess postoperative pain and its intensity a segmented numeric version of the visual analogue scale (VAS) is the score that used. The patient will select a whole number (0- 10 integers) that best reflects the intensity of his pain; 1-10 is recorded by a blinded investigator during 24 hours * All patients receive intravenous paracetamol IV/8 hours, Patients receive intravenous pethidine 0.5mg/kg as rescue analgesia when the VAS is equal or more than 4.

  During 24 hours

Study Arms (2)

Adductor canal block (ACB) only

ACTIVE COMPARATOR

This group will receive Adductor canal block only (control group)

Procedure: Adductor Canal Block (ACB) Only

Adductor canal block (ACB) combined with Genicular nerve block (GNB)

ACTIVE COMPARATOR

This group will receive Adductor canal block and Genicular nerve block

Procedure: Adductor canal block (ACB) combined with Genicular nerve block (GNB)

Interventions

Adductor Canal Block (ACB) Only PROCEDURE

All patients will receive adductor canal block under complete aseptic conditions using a high-frequency ultrasound guidance (Sonosite turbo M, Bothell, Washington,USA ). while patient is laying supine lower limbs will slightly abducted at the hips and flexed at the knees , using linear ultrasound probe(2.5-7.5MHZ) on the anterior aspect of the patient's thigh, At the level of mid-thigh, by moving probe medially until the boat shaped Sartorius muscle is visualized , at which the adductor canal is identified beneath the sartorius muscle, 20ml bupivacaine (0.25%) will be injected in the canal after a careful negative aspiration. The spread of the drug lateral and around the femoral artery will be seen real time on ultrasound

Adductor canal block (ACB) only

Adductor canal block (ACB) combined with Genicular nerve block (GNB) PROCEDURE

All patients will receive adductor canal block as described above under complete aseptic conditions then they will receive the genicular nerve block using a high-frequency ultrasound guidance (Sonosite turbo M, Bothell, Washington,USA ), genicular nerve block will be done at three locations, i.e., superomedial, superolateral, and inferomedial locations of the condyle-shaft junction, while patient is lying supine linear ultrasound probe(2.5-7.5MHZ) will be used to target the superomedial, superolateral, and inferomedial genicular nerves,2ml bupivacaine (0.25%) will be injected in the 3 mentioned points after a careful negative aspiration

Adductor canal block (ACB) combined with Genicular nerve block (GNB)

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Physical status: ASA 1 or 2 and candidates for knee arthroscopy.
• Age group: 18-50 years.
• No sex predilection.

You may not qualify if:

• Physical status: ASA III or above.
• Patients with a history of drug allergies to study drugs.
• Previous trauma or surgery to the leg.
• Opioids or alcohol abuse.
• Bleeding tendency.
• Dysesthesia, loss of sensation around the knee or medial aspect of the thigh.
• Inability to cooperate.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Egypt, 11111, Egypt

Location

MeSH Terms

Interventions

Single Person

Intervention Hierarchy (Ancestors)

Marital Status; Family Characteristics; Demography; Population Characteristics; Socioeconomic Factors

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 6, 2025
• First Posted: April 30, 2025
• Study Start: April 1, 2024
• Primary Completion: September 28, 2024
• Study Completion: September 28, 2024
• Last Updated: April 30, 2025

Record last verified: 2024-03

Locations

EG (1)