The Analgesic Effect of Ultrasound-guided Sacral Erector Spinae, Pericapsular Nerve Block and Lumber Plexus Block for Pain Relief for Hip Surgery: Randomized Controlled Study

NCT06842342 | Completed DMC

• 1 other identifier: 36264PR977
• Study Type: interventional
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study to evaluate the effect of The analgesic effect of Ultrasound-guided Sacral erector spinae, Pericapsular nerve block and Lumber Plexus block for pain relief after hip surgery. The primary outcome will be the collective morphine consumption on the 1st day post-operatively. Secondary end points Early postoperative pain scores including static pain and passive movement pain (at PACU, at 6 ,12,18 and 24 h after surgery) will be evaluated with visual analog scale (VAS) ranging from 0 to 10, where 0 means no pain and 10 means the worst pain Intraoperative consumption of fentanyl Intraoperative adverse reactions (hypotension, bradycardia, etc.) Complications related with anesthesia (local anesthetic systemic toxicity, pneumothorax, hematoma, etc.) Performance time of block (defined as the time from ultrasound scanning to the end of injection)

Conditions

Sacral Erector Block Versus Pericapsular Block Versus Lumber Plexus Block

Outcome Measures

Primary Outcomes (1)

• Morphine consumption over 24 hours

  will be the collective morphine consumption on the 1st day post-operatively

  24 hours postoperatively

Secondary Outcomes (1)

• Pain score

  During and after operation within 24 hours

Study Arms (3)

Group LPB

ACTIVE COMPARATOR

Procedure: Lumber plexus block

Group ESB

ACTIVE COMPARATOR

Procedure: Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)

Group PENG

ACTIVE COMPARATOR

Procedure: PENG Block

Interventions

Erector Spinae (ESP) Block with Bupivacaine (Marcaine®) PROCEDURE

ESB Group: All members of this group will receive ipsilateral sacral erector spinae block after induction of general anesthesia. The ESB will be performed by using 30 ml mixture of lidocaine 2% (10 ml), bupivacaine 0.25%(10 ml) and 10-mL normal saline will be injected at that point after repeated negative aspiration.

Group ESB

PENG Block PROCEDURE

PENG block: All members of this group will receive PENG block in the supine position after general anesthesia, The PENG will be performed by using 40 ml mixture of, 20 mL of 0.5 bupivacaine,10 mL of 2% lidocaine, and 10 mL of normal saline.

Group PENG

Lumber plexus block PROCEDURE

LPB Group: All members of this group will receive ipsilateral lumber plexus after induction of general anesthesia. The LPB will be performed by using 30 ml mixture of lidocaine 2% (10 ml), bupivacaine 0.25%(10 ml) and 10-mL normal saline will be injected at that point after repeated negative aspiration.

Group LPB

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged between 18 and 75 years old without cognitive dysfunction
• Body mass index (BMI) between 18.5 and 30 kg/m 2 and the weight ≥ 50 kg
• American Society of Anesthesiologists (ASA) classification I-II

You may not qualify if:

• Refuse to general anesthesia (GA) with tracheal intubation
• Nerve block is contraindicated due to various reasons, such as open trauma, hematoma or skin infection at the blocking area, lower limb neuro-muscular disorders
• Coagulation dysfunction or anticoagulation therapy
• Known hypersensitivity or allergy to local anesthetics

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta

Tanta, Tanta, 0020, Egypt

Location

MeSH Terms

Interventions

Parapsychology; Dental Occlusion; Bupivacaine

Intervention Hierarchy (Ancestors)

Behavioral Sciences; Behavioral Disciplines and Activities; Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena; Anilides; Amides; Organic Chemicals; Aniline Compounds; Amines

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesia, Surgical ICU and Pain Medicine

Study Record Dates

• First Submitted: February 8, 2025
• First Posted: February 24, 2025
• Study Start: January 10, 2025
• Primary Completion: June 10, 2025
• Study Completion: July 10, 2025
• Last Updated: January 13, 2026

Record last verified: 2026-01

Locations

EG (1)