NCT07326046

Brief Summary

This cross-sectional observational study investigated the relationships among dynamic Q angle, core muscle endurance, hip flexibility, and lower extremity functional status in elite adolescent athletes with and without patellofemoral pain syndrome (PFPS). A total of 75 track-and-field athletes aged 15-18 years were included, 42 with PFPS and 33 healthy controls. Dynamic Q angle was assessed using a digital goniometric analysis of the step-down test, core endurance was measured with the McGill endurance tests, flexibility was evaluated using the Straight Leg Raise, Modified Thomas, and Ober tests, and functional status was assessed with the Lower Extremity Functional Scale (LEFS). The study found that athletes with PFPS demonstrated a higher dynamic Q angle, lower core extension and lateral endurance, reduced hip flexor and iliotibial band flexibility, and lower functional scores compared with controls. Regression analyses indicated that hip flexor tightness and functional capacity were significant predictors of the dynamic Q angle in the PFPS group. These findings suggest that PFPS in adolescent athletes is a multidimensional condition influenced by proximal endurance, flexibility, and dynamic alignment rather than isolated knee-level factors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2025

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 16, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 25, 2025

Completed
14 days until next milestone

First Posted

Study publicly available on registry

January 8, 2026

Completed
Last Updated

January 13, 2026

Status Verified

January 1, 2026

Enrollment Period

7 months

First QC Date

December 25, 2025

Last Update Submit

January 11, 2026

Conditions

Keywords

Dynamic Q Angleore EnduranceLower Extremity FunctionAdolescent Athletes

Outcome Measures

Primary Outcomes (7)

  • Dynamic Q Angle

    Dynamic Q angle measured on the index limb during the step-down test using 2-dimensional digital goniometric video analysis. Higher values indicate greater frontal-plane malalignment.

    Single assessment at baseline (cross-sectional).

  • Core Muscle Endurance - Extension Test

    Duration (seconds) of trunk extensor endurance test from the McGill protocol. Longer duration reflects better endurance capacity.

    Single assessment at baseline.

  • Hip Flexor Flexibility - Modified Thomas Test

    Hip flexion angle obtained during the Modified Thomas test on the index limb. Greater angles indicate muscle tightness.

    Baseline, single assessment.

  • Core Muscle Endurance - Lateral Plank Test

    Duration (seconds) of lateral plank endurance on the index limb according to the McGill protocol.

    Single assessment at baseline.

  • Iliotibial Band / TFL Flexibility - Ober Test

    Adduction angle recorded during the Ober test on the index limb. Lower adduction indicates greater tightness.

    Baseline, single assessment.

  • Hamstring Flexibility - Straight Leg Raise Test

    Hip flexion angle at the onset of pelvic compensation during passive straight leg raise. Higher angles reflect better flexibility.

    Single assessment at baseline.

  • Functional Status - Lower Extremity Functional Scale (LEFS)

    Self-reported lower-limb functional capacity scored from 0-80, with higher scores indicating better function.

    Baseline, single assessment.

Study Arms (2)

PFPS Group/ Cohort

Adolescent elite athletes diagnosed with patellofemoral pain syndrome.

Control Group

Healthy adolescent elite athletes without anterior knee pain or lower extremity complaints.

Eligibility Criteria

Age15 Years - 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Elite adolescent track-and-field athletes training within national athletic development programs.

You may qualify if:

  • Elite adolescent track-and-field athletes aged 15-18 years
  • Minimum 2 years of regular training participation
  • Training at least 5 days per week
  • Ability to complete all assessment procedures
  • PFPS group: history of anterior knee pain associated with activity, positive clinical provocation tests, and AKPS score \< 80
  • Control group: no history of lower extremity pain or functional limitation

You may not qualify if:

  • History of lower extremity surgery or acute injury within the past 6 months
  • Neurological, rheumatological, or systemic disease
  • Structural deformity of the hip, knee, or ankle
  • Ongoing orthopedic rehabilitation or regular analgesic / anti-inflammatory medication use
  • Any condition preventing participation in the tests or introducing measurement bias

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Burcin Ugur Tosun

Famagusta, 99010, Cyprus

Location

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator PhD Physiotherapist Burcin Ugur Tosun

Study Record Dates

First Submitted

December 25, 2025

First Posted

January 8, 2026

Study Start

March 1, 2025

Primary Completion

September 15, 2025

Study Completion

October 16, 2025

Last Updated

January 13, 2026

Record last verified: 2026-01

Locations