NCT07289789

Brief Summary

Asthma is characterized by airway inflammation and hyperinflation that flattens the diaphragm and increases reliance on accessory neck muscles. Chronic overuse shortens these muscles and promotes forward head posture (FHP), which in turn compromises rib-cage motion and respiratory mechanics. Correcting FHP alongside breathing retraining may therefore improve lung function and symptoms in asthma. This interventional, parallel-group study investigates the combined effects of McKenzie neck exercises with two different breathing approaches on lung function, chest expansion, posture, and quality of life in adults with asthma. Participants are allocated to two groups for a 4-week program: Group A performs McKenzie neck exercises plus Pilates-based breathing; Group B performs McKenzie neck exercises plus Buteyko breathing.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
22

participants targeted

Target at below P25 for not_applicable asthma

Timeline
Completed

Started Aug 2025

Shorter than P25 for not_applicable asthma

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 20, 2025

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

September 12, 2025

Completed
3 months until next milestone

First Posted

Study publicly available on registry

December 17, 2025

Completed
15 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2026

Completed
Last Updated

December 17, 2025

Status Verified

December 1, 2025

Enrollment Period

4 months

First QC Date

September 12, 2025

Last Update Submit

December 4, 2025

Conditions

Keywords

Breathing exercisesRespiratory Function TestChest ExpansionMckenzie Neck Exercises

Outcome Measures

Primary Outcomes (2)

  • Chest Expansion

    Description: Chest expansion will be measured in centimeters using a standard measuring tape at the level of the 4th intercostal space.

    4 weeks

  • Lung Functions

    Lung function will be assessed using a spirometer. The parameters recorded will be FEV1 (Forced Expiratory Volume in 1 second), FVC (Forced Vital Capacity) and FEV1/FVC ratio.

    04 weeks

Study Arms (2)

McKenzie neck exercises with Pilates-based breathing

EXPERIMENTAL

Participants in this group will perform McKenzie neck exercises in combination with Pilates-based breathing techniques, along with their usual pharmacological management for asthma. The program will run for 4 weeks with progressive intensity. McKenzie exercises will start with 5 repetitions per exercise in Weeks 1-2 and progress to 10 repetitions in Weeks 3-4. Pilates breathing will begin with 2 sets of 10 repetitions in Weeks 1-2, progress to 3 sets in Week 3, and 4 sets in Week 4.

Procedure: Pilates Breathing Combined with McKenzie Neck Exercises

McKenzie neck exercises with Buteyko breathing technique

EXPERIMENTAL

Participants in this group will perform McKenzie neck exercises in combination with Buteyko breathing techniques, along with their usual pharmacological management for asthma. The program will run for 4 weeks with progressive intensity. McKenzie exercises will start with 5 repetitions per exercise in Weeks 1-2 and progress to 10 repetitions in Weeks 3-4. Buteyko breathing will begin with 2 sets of 10 repetitions in Weeks 1-2, progress to 3 sets in Week 3, and 4 sets in Week 4.

Procedure: McKenzie Neck Exercises with Buteyko Breathing

Interventions

Participants in this group will undergo a four-week intervention program combining McKenzie neck exercises with Pilates-based breathing techniques. The McKenzie exercises will be performed at an intensity of five repetitions per exercise during the first two weeks, progressing to ten repetitions per exercise in the third and fourth weeks. Pilates breathing will begin with two sets of ten repetitions in the first and second weeks, progress to three sets of ten repetitions in the third week, and further increase to four sets of ten repetitions in the fourth week. The intervention will be carried out three days per week on alternate days.

McKenzie neck exercises with Pilates-based breathing

Participants in this group will undergo a four-week intervention program combining McKenzie neck exercises with Pilates-based breathing techniques. The McKenzie exercises will be performed at an intensity of five repetitions per exercise during the first two weeks, progressing to ten repetitions per exercise in the third and fourth weeks. Pilates breathing will begin with two sets of ten repetitions in the first and second weeks, progress to three sets of ten repetitions in the third week, and further increase to four sets of ten repetitions in the fourth week. The intervention will be carried out three days per week on alternate days

McKenzie neck exercises with Buteyko breathing technique

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age group 18-40years
  • Both males and females
  • Individuals clinically diagnosed with asthma that is well controlled (Level 1 and Level 2) with FHP
  • Not participated in any structured exercise regime for improving lung function during the past 6 months.
  • Individuals well tolerated with a current exercise plan of combination exercises. (Buteyko breathing/Pilate breathing and McKenzie neck exercises

You may not qualify if:

  • Level 3 and 4 asthma or status asthmatics.
  • Any congenital deformity of the chest wall
  • Any active infections like fever, TB
  • Those with any contraindication to exercise testing or training.
  • Recent history of any chest wall trauma
  • Any abdominal or cardio thoracic surgery
  • Any psychiatric illness
  • Unstable Cardiopulmonary disease i.e. unstable angina, heart failure, recent MI.
  • Unstable hemodynamic parameters (arterial pressure \>140mmhg systolic and \>90mmhg for diastolic
  • Pregnancy
  • Previous or parallel participation in interventional programs.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Foundation University College of Physical Therapy, Islamabad, 44000

Islamabad, 44000, Pakistan

RECRUITING

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Central Study Contacts

Arzoo Bashir Awan, DPT

CONTACT

Sana Bashir, MS-CPPT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 12, 2025

First Posted

December 17, 2025

Study Start

August 20, 2025

Primary Completion

January 1, 2026

Study Completion

February 1, 2026

Last Updated

December 17, 2025

Record last verified: 2025-12

Locations