NCT07508280

Brief Summary

The aim of this study was to evaluate the Effects of energy conservation exercises versus circuit training on dyspnea, functional capacity and quality of life in asthmatic patients.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
32

participants targeted

Target at below P25 for not_applicable asthma

Timeline
Completed

Started Feb 2026

Shorter than P25 for not_applicable asthma

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2026

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 27, 2026

Completed
5 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2026

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 2, 2026

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2026

Completed
Last Updated

April 2, 2026

Status Verified

March 1, 2026

Enrollment Period

2 months

First QC Date

March 27, 2026

Last Update Submit

March 27, 2026

Conditions

Asthma

Keywords

AsthmaEnergy ConservationCircuit TrainingDiaphragmatic breathingFunctional Capacity

Outcome Measures

Primary Outcomes (1)

  • 6MWT

    Changes from baseline, is a safe, reliable, and valid tool for assessing functional exercise capacity in asthma patients, including those with severe, uncontrolled, or difficult-to-treat asthma.

    through study completion, approximately 4 weeks

Secondary Outcomes (2)

  • Modified Borg Dyspnea Scale

    through study completion, approximately 4 weeks

  • ST George questionnaire

    through study completion, approximately 4 weeks

Study Arms (2)

Energy conservation Technique

EXPERIMENTAL

Using energy conservation techniques to asthmatic patients in addition to standard treatment

Other: Energy Conservation Technique

Circuit Training

EXPERIMENTAL

Using circuit Training to asthmatic patients in addition to standard treatment

Other: Circuit Training

Interventions

Energy Conservation TechniqueOTHER

Energy conservation technique is used to focus on reducing physical fatigue and improving daily functioning through pacing, planning, prioritizing, and simplifying tasks. 1\. After breathing exercise as a baseline 2. Dictate some activities like that on first patient use more energy expenditure than less it might be his ADL's

Energy conservation Technique
Circuit TrainingOTHER

Circuit training is a series of exercises that involve little or no rest between repetitions. it is a resistance training for asthmatic patients at their pace. After warm up patient move to next station which consumed higher H.R After that move to resting period like using or working on low H.R

Circuit Training

Eligibility Criteria

Age30 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • \- Subjects with asthma diagnosis grade according to FEV 60%-80%

You may not qualify if:

  • Pregnancy
  • Previous breathing exercise training
  • Severe comorbidity
  • Patients with short life expectancy
  • subjects with Severe physical impairments
  • Subjects with Mental disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Doctor's hospital

Jhang, Punjab Province, 35200, Pakistan

RECRUITING

Related Publications (21)

  • Hammad H, Lambrecht BN. The basic immunology of asthma. Cell. 2021;184(6):1469-85.

    BACKGROUND

  • Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, et al. Multiview cluster analysis identifies variable corticosteroid response phenotypes in severe asthma. American journal of respiratory and critical care medicine. 2019;199(11):1358-67.

    BACKGROUND

  • Thomas D, McDonald VM, Pavord ID, Gibson PG. Asthma remission: what is it and how can it be achieved? European Respiratory Journal. 2022;60(5).

    BACKGROUND

  • Young TW. Fatal bronchial asthma with bilateral lung collapse. The American Journal of Forensic Medicine and Pathology. 2010;31(4):373-5.

    BACKGROUND

  • Shahid S, Rafique S, Shakoor AA, Sheraz M, Aamir R, Safder M, et al. A systematic review of prescription patterns and cost of treatment in Asthma management in Asian countries. Medical Science. 2024;28:e33ms3328.

    BACKGROUND

  • Wingårdh ASL, Göransson C, Larsson S, Slinde F, Vanfleteren LE. Effectiveness of energy conservation techniques in patients with COPD. Respiration. 2020;99(5):409-16.

    BACKGROUND

  • Prieur G, Combret Y, Medrinal C, Arnol N, Bonnevie T, Gravier F-E, et al. Energy conservation technique improves dyspnoea when patients with severe COPD climb stairs: a randomised crossover study. Thorax. 2020;75(6):510-2.

    BACKGROUND

  • Kozu R, Shingai K, Hanada M, Oikawa M, Nagura H, Ito H, et al. Respiratory impairment, limited activity, and pulmonary rehabilitation in patients with interstitial lung disease. Physical Therapy Research. 2021;24(1):9-16.

    BACKGROUND

  • Cazorla S, Busegnies Y, D'Ans P, Héritier M, Poncin W, editors. Breathing control exercises delivered in a group setting for patients with chronic obstructive pulmonary disease: a randomized controlled trial. Healthcare; 2023: MDPI.

    BACKGROUND

  • Mazzarin CM, Silveira BR, Lamezon AC, Cavon Luna B, Valderramas S. Effectiveness and Safety of Multicomponent Physical Training in Patients With Chronic Obstructive Pulmonary Disease: Protocol for a Randomized Clinical Trial. Health Services Insights. 2023;16:11786329231169255.

    BACKGROUND

  • Klimczak MK, Krzepkowski HA, Piotrowski WJ, Białas AJ. The Short-Term Efficacy of a Three Week Pulmonary Rehabilitation Program among Patients with Obstructive Lung Diseases. Journal of Clinical Medicine. 2024;13(9):2576.

    BACKGROUND

  • Solanke AV, Lajwanti L. Incorporating RC-Cornet PLUS and POWERbreathe Medic Plus Device Along With Pulmonary Rehabilitation on Functional Capacity and Quality of Life in Bronchiectasis: A Case Report. Cureus. 2025;17(2).

    BACKGROUND

  • Bruton A, Lee A, Yardley L, Raftery J, Arden-Close E, Kirby S, et al. Physiotherapy breathing retraining for asthma: a randomised controlled trial. The Lancet Respiratory Medicine. 2018;6(1):19 28.

    BACKGROUND

  • Sosa-Pedreschi A, Donadio MVF, Iturriaga-Ramírez T, Yvert T, Pérez-Salazar F, Santiago-Dorrego C, et al. Effects of a remotely supervised resistance training program on muscle strength and body composition in adults with cystic fibrosis: Randomized controlled trial. Scandinavian Journal of Medicine & Science in Sports. 2024;34(1):e14564.

    BACKGROUND

  • Yasar Kucukardali M. Effects of Neuromuscular Electrical Stimulation on Muscle Strength, Functional Capacity, and Quality of Life Among Older Patients With Asthma. Alternative Therapies in Health and Medicine. 2024;30(6):6-15.

    BACKGROUND

  • Andreasson KH, Skou ST, Ulrik CS, Madsen H, Sidenius K, Assing KD, et al. Breathing exercises for patients with asthma in specialist care: a multicenter randomized clinical trial. Annals of the American Thoracic Society. 2022;19(9):1498-506.

    BACKGROUND

  • Yu-Lin AB. The benefits of early pulmonary rehabilitation with incentive spirometer among chronic obstructive pulmonary disease patients with exacerbation of chronic obstructive pulmonary disease. Med J Malaysia. 2024;79(5):561.

    BACKGROUND

  • Reychler G, Beaumont M, Latiers A-C, Pieters T, Fremault A. Dyspnea could be accurately assessed by a caregiver in hospitalized patients with respiratory diseases: Interrater reliability and agreement study. Brazilian journal of physical therapy. 2021;25(6):735-40.

    BACKGROUND

  • Ferrer M, Villasante C, Alonso J, Sobradillo V, Gabriel R, Vilagut G, et al. Interpretation of quality of life scores from the St George's Respiratory Questionnaire. European Respiratory Journal. 2002;19(3):405-13.

    BACKGROUND

  • Carson KV, Chandratilleke MG, Picot J, Brinn MP, Esterman AJ, Smith BJ. Physical training for asthma. Cochrane Database of Systematic Reviews. 2013(9).

    BACKGROUND

  • Klika B, Jordan C. High-intensity circuit training using body weight: Maximum results with minimal investment. ACSM's Health & Fitness Journal. 2013;17(3):8-13.

    BACKGROUND

MeSH Terms

Conditions

Asthma

Interventions

Circuit-Based Exercise

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Qurat ul Ain

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Dr Imran Amjad, PhD

CONTACT

(+92) 03324390125imran.amjad@riphah.edu.pk

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 27, 2026

First Posted

April 2, 2026

Study Start

February 1, 2026

Primary Completion

April 1, 2026

Study Completion

May 1, 2026

Last Updated

April 2, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)