Alternate Nostril Breathing With Incentive Spirometry on Lung Function Among Asthma Patients

NCT07110116 | Recruiting DMC

• 1 other identifier: REC/02192 Hira Qazi
• Study Type: interventional
• Target: 54
• Locations: 1 country
• Sites: 1

Brief Summary

To compare effects of Alternate Nostril Breathing exercise with incentive spirometer on lung functions (forced vital capacity, forced expiratory volume, and peak expiratory flow rate) in Asthma patients.

Conditions

Asthma

Outcome Measures

Primary Outcomes (5)

• Forced expiratory volume in 1 second

  Forced Expiratory Volume in 1 second (FEV1) is a measurement of how much air a person can forcefully exhale from their lungs in one second

  6 week

• Forced Vital Capicity

  Forced vital capacity (FVC) is a measurement of lung function that quantifies the maximum amount of air a person can forcefully exhale after taking the deepest breath possible

  6 week

• Peak Expiratory Flow Rate

  Peak expiratory flow rate (PEFR) measures the maximum speed of air that a person can forcefully exhale in one breath

  6 week

• Asthama Control Test

  The Asthma Control Test (ACT) is scored by assigning a value from 1 to 5 to each response in the 5-question survey, then summing these values for a total score ranging from 5 to 25. A higher score indicates better asthma control. A score of 20 or higher generally suggests well-controlled asthma.

  6 week

• Asthama Quality of Life Questionaire with standardized Activities

  The Standardized Asthma Quality of Life Questionnaire (AQLQ(S)) is a 32-item questionnaire used to assess the impact of asthma on an individual's quality of life, specifically focusing on the physical, emotional, and social aspects. 7-point Likert scale (7 = not impaired at all - 1 = severely impaired). Scores range 1-7, with higher scores indicating better quality of life.

  6 week

Study Arms (2)

Alternate nostril breathing with Incentive Spirometery

EXPERIMENTAL

Other: Alternate nostril breathing with Incentive Spirometery

Incentive Spirometery

ACTIVE COMPARATOR

Other: Incentive spirometery

Interventions

Alternate nostril breathing with Incentive Spirometery OTHER

Participants in experimental group were instructed to close their left nostril by left index finger and inhale through their right nostril for six seconds, then closing the right nostril and holding breath for six seconds. Afterward, they exhaled through the left nostril slowly for six seconds. Next, they inhaled through left nostril, keeping the right nostril closed for six seconds then hold the breath by closing both nostrils for six seconds subsequently, and then exhaled through the right nostril, keeping the left closed for six seconds repeating these steps several times for 10 minutes

Alternate nostril breathing with Incentive Spirometery

Incentive spirometery OTHER

The control group participants were asked to do breathing exercise with incentive spirometry. The subject is asked to create a tight seal around the mouthpiece and asked to inhale deeply and slowly and the subject would observe the flow meter for visual feedback of his/her effort. At the end of the inspiration the subject is asked to sustain the inhalation 2-3 seconds to facilitate the Inspiratory hold. Subject relaxes the seal around the mouthpiece and exhales. Normal breathing is taken, then the exhalation phase in the incentive spirometry is done and the whole cycle is repeated 5 - 10 times thrice a day over a period 6 weeks

Incentive Spirometery

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Diagnosed male \& female asthma patients of age 18-60 years.
• Patients with mild to moderate asthma having predicted FEV1 between 60-80%.
• Stable asthma condition without recent exacerbations.
• Able to perform spirometry and follow instructions for the interventions.
• No recent respiratory infections.

You may not qualify if:

• Patients with severe asthma (FEV1 \< 60% predicted).
• Patients having respiratory infections, recent exacerbations or other comorbidities.
• Inability to perform breathing exercises or spirometry.
• Patients using medications like oral steroids, beta blockers.
• Pregnant women due to potential risks with breathing exercises.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Allied Specialist Hospital & Clinics

Abbottābād, Khyber PkahtoonKhwa, 22020, Pakistan

RECRUITING

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Officials

• Muhammad Iqbal Tariq, PhD*

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Muhammad Iqbal Tariq, PhD*

CONTACT

03338236752; iqbal.tariq@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 31, 2025
• First Posted: August 7, 2025
• Study Start: August 20, 2025
• Primary Completion: November 1, 2025
• Study Completion: November 1, 2025
• Last Updated: September 5, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)