Combined Effects Of Diaphragm Strengthening And Accessory Muscles Stretchings In Asthma Patients

NCT05915793 | Unknown

• 1 other identifier: REC/RCR&AHS/23/0315
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

Asthma is a multifactorial and chronic inflammatory disease in older patients affecting many people worldwide with high cost of pharmacological treatment and physiotherapy interventions. It is characterized by a variety of symptoms including airway inflammation, bronchial hyper-responsiveness, and transient and reversible airway obstruction. Typical clinical features include wheezing, coughing, resting and/or exertional dyspnea, and chest tightness. Lung hyperinflation affects ability to inspire and increases the work of breathing. Long and short acting corticosteroids and leukotriene are considered effective pharmacological interventions while inspiratory muscle training, incentive spirometry, purse lip breathing, and diaphragm strengthening are considered effective physiotherapy interventions for asthma patients. To find the combined effects of diaphragm strengthening and accessory muscle stretching on chest expansion, pulmonary function, dyspnea and exercise capacity in asthmatic patients. A randomized controlled trial will be conducted at Gulab Davi teaching Hospital Lahore through convenient sampling technique on 40 patients which will be allocated through concealed opaque envelop into Group A and Group Pretreatment values of pulmonary function and chest expansion will be recorded. And patient's perception of exertion through Modified Borg's rating of perceived exertion (RPE) and HRQOL for quality of life will be assessed before and after treatment. Group A will be treated with diaphragm strengthening and Group B will be treated with diaphragm strengthening and accessory muscles stretching. Treatment evaluation will be done after 4 weeks. Data will be analyzed using SPSS software version 25. After assessing normality of data by Shapiro-Wilk test, it will be decided either parametric or non-parametric test will be use within a group or between two groups.

Conditions

Asthma

Outcome Measures

Primary Outcomes (2)

• Modified Borg scale of exertion

  The Modified Borg Dyspnea Scale (MBS) is a 0 to 10 rated numerical score used to measure dyspnea as reported by the patient during submaximal exercise and is routinely administered during six-minute walk testing (6MWT)

  6 weeks

• 6 MWT

  The 6MWT was used to detect participants' functional capacity by measuring the distance they traveled during the walk test. For the 6MWT assessment, the participants were encouraged to walk as far as they could during 6 min over a flat 100-feet surface, and for consistency, the researchers used constant verbal cues and positive feedback to encourage the participants to complete the task

  6 weeks

Secondary Outcomes (1)

• Quality of life questionnaire

  6 weeks

Study Arms (2)

Diaphragm strengthening and accessory muscles stretchings

EXPERIMENTAL

Other: Diaphragm strengthening and accessory muscles stretchings

Diaphragm strengthening

ACTIVE COMPARATOR

Other: Diaphragm strengthening

Interventions

Diaphragm strengthening and accessory muscles stretchings OTHER

Diaphragm strengthening and accessory muscles stretchings

Diaphragm strengthening and accessory muscles stretchings

Diaphragm strengthening OTHER

Diaphragm strengthening

Diaphragm strengthening

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age group of 40-65 years
• Both male and females
• Phase-2 asthma patients
• Patients hemodynamically stable

You may not qualify if:

• Patients having pulmonary tumors
• Patients of Having cough and sputum
• Patients having TB and emphysema
• Patients with pneumonia, pneumonectomy or other lungs surgical procedures

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Gulab Devi Hospital

Lahore, Punjab Province, 54000, Pakistan

RECRUITING

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MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Officials

• Ameena Amjad, tDPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Imran Amjad, Phd

CONTACT

03324390125; imran.amjad@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 14, 2023
• First Posted: June 23, 2023
• Study Start: February 1, 2023
• Primary Completion: August 29, 2023
• Study Completion: August 29, 2023
• Last Updated: June 23, 2023

Record last verified: 2023-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)