Impact of an e-Bug Educational Intervention on HPV Vaccine Uptake in Middle School Students

NCT07266857 | Recruiting

• 1 other identifier: 25SantéMentale02
• Study Type: observational
• Target: 11,000
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a non-interventional observational pilot analysis assessing the possible impact of an educational programme (e-Bug) on parental consent and HPV vaccination uptake during the 2023-2024 and 2024-2025 national school-based HPV vaccination campaigns in France. The study focuses on one middle school in the Alpes-Maritimes department where teachers and the school nurse had been previously trained on HPV and used e-Bug educational resources in class as part of routine health education. No research-related intervention was conducted, and the educational programme was not introduced or modified for the purpose of the study. Only aggregated and anonymised vaccination data were used. These data were routinely collected by the Regional Health Agency (ARS PACA) as part of the national vaccination programme and transmitted for analysis. Aggregated data from the pilot school were compared with departmental-level outcomes to describe whether an upstream educational approach may be associated with improved parental acceptance and higher HPV vaccination coverage. This study aims to contribute to the understanding of educational determinants of vaccine uptake in a real-life school setting without involving any participant recruitment or individual data collection.

Conditions

Papillomavirus Infection; Papillomavirus Vaccines; Vaccination Coveage

Outcome Measures

Primary Outcomes (1)

• HPV vaccination uptake (1st and 2nd doses) in the pilot school compared with departmental data

  e-Bug educational programme

  From (start of 2023-2024 HPV vaccination campaign) to(end of 2024-2025)

Secondary Outcomes (2)

• Parental consent rate (acceptability)

  From (start of 2023-2024 HPV vaccination campaign) to(end of 2024-2025)

• Response rate (return of vaccination authorisation forms)

  From (start of 2023-2024 HPV vaccination campaign) to(end of 2024-2025)

Study Arms (2)

Pilot School Using e-Bug Programme

Other: Consent for HPV vaccination

Other Middle Schools in Alpes-Maritimes Department

Other: Consent for HPV vaccination

Interventions

Consent for HPV vaccination OTHER

Consent for HPV vaccination

Other Middle Schools in Alpes-Maritimes Department; Pilot School Using e-Bug Programme

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Aggregated data from 5th-grade students enrolled in one pilot middle school using the e-Bug programme, compared with aggregated data from all other middle schools in the Alpes-Maritimes department. No individual-level data were accessed.

You may qualify if:

• No individual participants are enrolled. The study uses only aggregated, anonymised vaccination data routinely collected by ARS PACA

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

Study Sites (1)

CHU de NICE

Nice, Alpes Maritimes, 06000, France

RECRUITING

MeSH Terms

Conditions

Papillomavirus Infections

Interventions

Consent Forms

Condition Hierarchy (Ancestors)

Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Communicable Diseases; Infections; DNA Virus Infections; Virus Diseases; Tumor Virus Infections; Genital Diseases; Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Informed Consent; Jurisprudence; Social Control, Formal; Health Care Economics and Organizations; Records; Organization and Administration; Health Services Administration; Data Collection; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation

Central Study Contacts

Laure Hermet

CONTACT

0492039007; hermet.l@chu-nice.fr

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 25, 2025
• First Posted: December 5, 2025
• Study Start: May 1, 2025
• Primary Completion: June 30, 2025
• Study Completion: December 31, 2025
• Last Updated: December 5, 2025

Record last verified: 2025-11

Locations

FR (1)