Study of the Optimal Number of Repetitions to Investigate the Cerebral Activity by fNIRS During a Voluntary Movement and an Illusory Movement Induced by Vibration

NCT07203807 | Completed

• 1 other identifier: CHUO-2025-17
• Study Type: observational
• Target: 29
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate the cerebral activation of healthy participants during a voluntary movement and an illusory movement induced by vibration. This will be done by repeating both tasks 20 times for 10 seconds. The study aims to determine the minimum number of repetitions (blocks) required to maximize cerebral activity.

Conditions

Healthy

Keywords

fNIRS; Blocks; Movement; Illusion

Outcome Measures

Primary Outcomes (2)

• Cerebral hemodynamic variations in the sensorimotor areas assessed by fNIRS with 42 long channels and 4 short channels.

  HbO will be considered as the primary outcome measure of the cerebral activity through the hemodynamic response

  Day 0

• Cerebral hemodynamic variations in the frontoparietal areas assessed by fNIRS with 42 long channels and 4 short channels

  HbO will be considered as the primary outcome measure of the cerebral activity through the hemodynamic response

  Day 0

Study Arms (1)

Healthy young

Healthy young participants aged 18 to 40

Other: Voluntary movement and illusory movement of the right upper limb induced by TVS.

Interventions

Voluntary movement and illusory movement of the right upper limb induced by TVS. OTHER

The protocol comprises two different modalities: Voluntary movement and illusory movement of the right upper limb induced by TVS. The experiment will begin and end with a one-minute rest period. Participants will be asked to open and close their right hand 20 times in 10 seconds. Similarly, they will experience 10 seconds of TVS-induced illusory movement 20 times. Each task epoch will be preceded by a 12-20 second resting period. Both conditions will be randomized and counterbalanced. Participants can start with either the voluntary movement task or the illusory.

Healthy young

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Healthy young adult aged 18 to 40

You may qualify if:

• Healthy volunteers aged 18 to 40
• Right-handed: Edinburgh laterality test short format QL \> 60 (Veale et al., 2014).
• Sufficient command of the French language to understand instructions
• No known neurological medical history

You may not qualify if:

• Allergy to neoprene (fNIRS cap material)
• Hair volume preventing the cap from fitting and/or access to the scalp
• Injury to right upper limb causing pain during mobilization
• Protected person (under guardianship or trusteeship)
• Person under court protection
• Persons deprived of liberty
• Persons not affiliated to a social security scheme
• Pregnant or breast-feeding women
• Volunteers opposed to the study

Sponsors & Collaborators

• Centre Hospitalier Régional d'Orléans: lead

Study Sites (1)

CHU Orléans

Orléans, 45067, France

Location

Related Publications (5)

• Edin BB, Vallbo AB. Dynamic response of human muscle spindle afferents to stretch. J Neurophysiol. 1990 Jun;63(6):1297-306. doi: 10.1152/jn.1990.63.6.1297.

  PMID: 2141632 BACKGROUND

• Herold F, Wiegel P, Scholkmann F, Thiers A, Hamacher D, Schega L. Functional near-infrared spectroscopy in movement science: a systematic review on cortical activity in postural and walking tasks. Neurophotonics. 2017 Oct;4(4):041403. doi: 10.1117/1.NPh.4.4.041403. Epub 2017 Aug 1.

  PMID: 28924563 BACKGROUND

• Naito E, Morita T, Amemiya K. Body representations in the human brain revealed by kinesthetic illusions and their essential contributions to motor control and corporeal awareness. Neurosci Res. 2016 Mar;104:16-30. doi: 10.1016/j.neures.2015.10.013. Epub 2015 Nov 10.

  PMID: 26562333 BACKGROUND

• Pinti P, Tachtsidis I, Hamilton A, Hirsch J, Aichelburg C, Gilbert S, Burgess PW. The present and future use of functional near-infrared spectroscopy (fNIRS) for cognitive neuroscience. Ann N Y Acad Sci. 2020 Mar;1464(1):5-29. doi: 10.1111/nyas.13948. Epub 2018 Aug 7.

  PMID: 30085354 BACKGROUND

• Schneider C, Marquis R, Johr J, Lopes da Silva M, Ryvlin P, Serino A, De Lucia M, Diserens K. Disentangling the percepts of illusory movement and sensory stimulation during tendon vibration in the EEG. Neuroimage. 2021 Nov 1;241:118431. doi: 10.1016/j.neuroimage.2021.118431. Epub 2021 Jul 28.

  PMID: 34329723 BACKGROUND

MeSH Terms

Conditions

Bites and Stings; Illusions

Condition Hierarchy (Ancestors)

Poisoning; Chemically-Induced Disorders; Wounds and Injuries; Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 25, 2025
• First Posted: October 2, 2025
• Study Start: October 27, 2025
• Primary Completion: October 31, 2025
• Study Completion: October 31, 2025
• Last Updated: January 8, 2026

Record last verified: 2026-01

Locations

FR (1)