Evaluation of Thyroid Function, Lipid Profile, and Uric Acid Levels in Hemodialysis Patients

NCT07157267 | Not Yet Recruiting

• 1 other identifier: Hemodialysis Patients
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

This observational study evaluates the prevalence and relationships of thyroid dysfunction, lipid abnormalities, and elevated uric acid levels in adult patients undergoing maintenance hemodialysis at Assiut University Hospital.

Conditions

Thyroid Dysfunction; Hemodialysis; Elevated Uric Acid

Keywords

hemodialysis; elevated uric acid; Thyroid Function Status

Outcome Measures

Primary Outcomes (1)

• Thyroid Function Status

  Assessment of the prevalence and types of thyroid dysfunction in hemodialysis patients

  baseline

Study Arms (1)

The study population consists of adult patients aged 18 years or older, undergoing regular hemodialy

The study involves 100 adult patients (≥18 years) who are on maintenance hemodialysis for three months or more. Patients with any known thyroid disorder prior to starting dialysis, those receiving lipid-lowering agents or uric acid-lowering medications, and those recently hospitalized or with acute infections in the last month are excluded. The population reflects a typical CKD hemodialysis demographic seen at Assiut University Hospital and includes diverse participants with varying ages, genders, smoking histories, and comorbid conditions such as diabetes mellitus and hypertension. Clinical and demographic data will be systematically gathered, including dialysis durations and adequacy, to provide comprehensive insights into the interplay of thyroid, lipid, and uric acid metabolism in these patients.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

the study population consists of adult patients aged 18 years or older, undergoing regular hemodialysis treatment at Assiut University Hospital for a minimum of three months, excluding those with pre-existing thyroid disorders or on relevant medications.

You may qualify if:

• Adults ≥18 years
• On regular hemodialysis for ≥3 months

You may not qualify if:

• On lipid-lowering or uric acid-lowering medications
• Acute infections or hospitalizations in the past month

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• Liu WC, Tomino Y, Lu KC. Impacts of uric acid on chronic kidney disease progression: a review. J Adv Res. 2017;8(5):449-56.

  BACKGROUND

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at the Internal Medicine Department

Study Record Dates

• First Submitted: August 28, 2025
• First Posted: September 5, 2025
• Study Start (Estimated): July 1, 2026
• Primary Completion (Estimated): October 30, 2027
• Study Completion (Estimated): December 30, 2027
• Last Updated: September 5, 2025

Record last verified: 2025-08