Periodontal Health and Quality of Life in Psoriasis Patients

NCT07154420 | Completed

• 1 other identifier: GUSTAOGLU
• Study Type: observational
• Target: 226
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the relationship between psoriasis, a chronic inflammatory skin disease, and oral health. We will assess the periodontal (gum) condition of patients with psoriasis and examine how it affects their quality of life. A group of psoriasis patients and a control group without psoriasis will undergo oral examinations and complete a short questionnaire. The goal is to better understand whether psoriasis has an impact on gum health and daily well-being.

Conditions

Psoriasis; Periodontal Diseases

Keywords

psoriasis,periodontitis

Outcome Measures

Primary Outcomes (1)

• Evaluation of oral health-related quality of life in psoriasis patients

  The Turkish version of the OHIP-14 questionnaire was administered through face-to-face interviews by a single investigator (G.U.), who was blinded to the periodontal status of the participants. The OHIP-14 consists of seven subscales, each including two items: functional limitation, physical pain, psychological discomfort, physical disability, psychological disability, social disability, and handicap. Participants rated the frequency of negative experiences on a five-point Likert scale (0 = never, 1 = rarely, 2 = occasionally, 3 = quite often, 4 = very often). The total score ranges from 0 to 56, with higher scores reflecting a greater negative impact on oral health-related quality of life

  Baseline

Secondary Outcomes (1)

• Evaluation of dermatology-specific quality of life in psoriasis patients

  Baseline

Study Arms (2)

psoriasis patient group

Diagnostic Test: Diagnostic Test: Periodontal Examination

healthy control group

Diagnostic Test: Diagnostic Test: Periodontal Examination

Interventions

Diagnostic Test: Periodontal Examination DIAGNOSTIC_TEST

Diagnostic Test: Periodontal Examination

healthy control group; psoriasis patient group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants aged 18 to 65 years, clinically diagnosed with active psoriasis, and applying to the Dermatology and Venereal Diseases Department outpatient clinic of the Gulhane Faculty of Medicine were recruited into the test group (n=113). The control group consisted of healthy individuals without any dermatological or systemic diseases (n=113).

You may qualify if:

• Participants aged 18 to 65 years
• Clinically diagnosed with active psoriasis
• The presence of at least 12 teeth (excluding third molars)
• Absence of contraindications for periodontal clinical examination

You may not qualify if:

• Other dermatological conditions
• Pregnancy or lactation
• Antibiotic use within the last 3 months
• Chemotherapy or radiotherapy within the last year
• Periodontal treatment within the last 6 months

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead

Study Sites (1)

Sağlık Bilimleri Üniversitesi

Ankara, Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Psoriasis; Periodontal Diseases; Periodontitis

Condition Hierarchy (Ancestors)

Skin Diseases, Papulosquamous; Skin Diseases; Skin and Connective Tissue Diseases; Mouth Diseases; Stomatognathic Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor

Study Record Dates

• First Submitted: August 19, 2025
• First Posted: September 4, 2025
• Study Start: April 20, 2025
• Primary Completion: July 20, 2025
• Study Completion: July 20, 2025
• Last Updated: September 4, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)