Green Tea Extract and Ginger

NCT07150533 | Completed

• 1 other identifier: ETU-Green Tea and Ginger
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the effects of green tea extract and ginger supplementation, both individually and in combination, on endurance performance, metabolism, thermal comfort, and muscle soreness in recreationally active young men. Participants will complete cycling tests under both normal room temperature (21-24°C) and cold (5-7°C) conditions. The study uses a randomized, double-blind, placebo-controlled, crossover design to compare the outcomes of placebo, green tea, ginger, and combined supplementation. The findings may help to identify nutritional strategies that improve exercise performance and comfort in different environmental conditions.

Conditions

Nutritional Supplementation; Exercise Physiology

Outcome Measures

Primary Outcomes (1)

• Time to Exhaustion (TTE)

  Endurance performance assessed as the total time in seconds participants are able to maintain cycling at 70% of VO₂max on a cycle ergometer, until volitional exhaustion defined as the inability to sustain a cadence of 60 rpm for 10 consecutive seconds

  Immediately during each exercise test session (after supplement ingestion, under normal and cold environmental conditions)

Study Arms (4)

Placebo Arm

PLACEBO COMPARATOR

Participants receive a placebo consisting of maltodextrin in capsule form, matched in appearance and taste to the active supplements.

Dietary Supplement: Placebo Arm

Green Tea Extract Arm

EXPERIMENTAL

Participants receive 500 mg of standardized green tea extract in capsule form.

Dietary Supplement: Green Tea Extract

Ginger Arm

EXPERIMENTAL

Participants receive 1 g of ginger supplement in capsule form.

Dietary Supplement: Ginger

Combined Supplement Arm

EXPERIMENTAL

Participants receive a combination of 500 mg green tea extract and 1 g ginger, both administered in capsule form.

Dietary Supplement: Combined Supplement (Green Tea + Ginger)

Interventions

Placebo Arm DIETARY_SUPPLEMENT

Participants receive a placebo consisting of maltodextrin in capsule form, matched in appearance and taste to the active supplements.

Placebo Arm

Green Tea Extract DIETARY_SUPPLEMENT

Participants receive 500 mg of standardized green tea extract in capsule form.

Green Tea Extract Arm

Ginger DIETARY_SUPPLEMENT

Participants receive 1 g of ginger supplement in capsule form.

Ginger Arm

Combined Supplement (Green Tea + Ginger) DIETARY_SUPPLEMENT

Participants receive a combination of 500 mg green tea extract and 1 g ginger, both administered in capsule form.

Combined Supplement Arm

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male participants aged 18-35 years
• Recreationally active (≥3 aerobic exercise sessions per week, ≥30 minutes per session, for at least 6 months)
• VO₂max between 40-50 mL/kg/min (recreationally active fitness level)
• Body mass index within the normal to slightly overweight range (approximately 18.5-27.5 kg/m²)
• Willingness to comply with study requirements, including supplementation and exercise testing protocols
• Provided written informed consent

You may not qualify if:

• History of cardiovascular, respiratory, metabolic, or neurological disorders
• Allergy or intolerance to green tea, ginger, or maltodextrin
• Current use of ergogenic supplements, medications affecting metabolism, or stimulants (e.g., beta-blockers, caffeine pills)
• Smoking or excessive alcohol consumption (\>14 units per week)
• Inconsistent exercise habits (\<3 sessions/week in the past 6 months)
• Participation in another clinical trial within the past 3 months

Sponsors & Collaborators

• Erzurum Technical University: lead

Study Sites (1)

Erzurum Technical University Sport Sciences Faculty

Erzurum, Erzurum, 25240, Turkey (Türkiye)

Location

Related Publications (1)

• Demirli A, Ulupinar S, Terzi M, Ozbay S, Ozkara AB, Gencoglu C, Ouergui I, Ardigo LP. Synergistic Effects of Green Tea Extract and Ginger Supplementation on Endurance Performance and Thermal Perception in Normothermic and Cold Environments: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial. Nutrients. 2025 Sep 13;17(18):2949. doi: 10.3390/nu17182949.

  PMID: 41010475 DERIVED

MeSH Terms

Interventions

Tea; ginger extract

Intervention Hierarchy (Ancestors)

Plant Preparations; Biological Products; Complex Mixtures; Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Exercise Physiology

Study Record Dates

• First Submitted: August 25, 2025
• First Posted: September 2, 2025
• Study Start: March 1, 2025
• Primary Completion: July 1, 2025
• Study Completion: July 30, 2025
• Last Updated: September 2, 2025

Record last verified: 2025-08

Locations

TU (1)