Jackfruit Effects on Adipokines and Cognition in Boxers

NCT07268976 | Completed DMC

• 1 other identifier: BU-2025-01
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the effects of jackfruit oil extract on adipokine levels (Irisin, Omentin-1), brain-derived neurotrophic factor (BDNF), cognitive performance, and body measurements in healthy young boxers aged 18-25. Participants were randomly assigned to four groups receiving different doses of jackfruit oil extract (0, 100, 200, 300 mg/kg) or no supplement. Saliva samples, cognitive tests, and body measurements were collected at the start of the study and after 30 days to evaluate the outcomes.

Conditions

Exercise Physiology; Cognitive Function; Adipokine Response; Irisin; Omentin-1; Brain-Derived Neurotrophic Factor (BDNF)

Keywords

Boxer; Athletes; Jackfruit; Irisin; Omentin-1; BDNF; Cognitive Performance; Anthropometric Measurements; Adipokines; Trail Making Test; Wisconsin Card Sorting Test (WCST); Body Composition

Outcome Measures

Primary Outcomes (3)

• Salivary Irisin Level

  Irisin levels measured from saliva samples collected from participants using the ELISA method.

  Day 0 and Day 30

• Salivary Omentin-1 Level

  Omentin-1 levels measured from saliva samples collected from participants using the ELISA method.

  Day 0 and Day 30.

• Salivary BDNF Level

  BDNF levels measured from saliva samples collected from participants using the ELISA method.

  Day 0 and Day 30.

Secondary Outcomes (28)

• Body Weight (kg)

  Day 0 and Day 30

• Height (cm)

  Day 0 and Day 30

• Body Mass Index (kg/m²)

  Day 0 and Day 30

• Waist Circumference (cm)

  Day 0 and Day 30

• Hip Circumference (cm)

  Day 0 and Day 30

Study Arms (4)

J0 - Kontrol Grubu

NO INTERVENTION

Katılımcılar hiçbir jackfruit yağı ekstresi almadı. Sadece normal diyet ve antrenman programlarını sürdürdüler.

J100

EXPERIMENTAL

Katılımcılara 100 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı.

Dietary Supplement: Jackfruit Supplement

J200

EXPERIMENTAL

Katılımcılara 200 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı.

Dietary Supplement: Jackfruit Supplement

J300

EXPERIMENTAL

Katılımcılara 300 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı.

Dietary Supplement: Jackfruit Supplement

Interventions

Jackfruit Supplement DIETARY_SUPPLEMENT

Participants in the experimental group will receive a daily dose of jackfruit supplement during the study period. The supplement is administered orally and standardized for bioactive components. Participants in the control group will not receive any jackfruit supplement.

J100; J200; J300

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male boxers aged 18-25 years
• Healthy individuals without any diagnosed chronic disease
• Participating in regular weekly boxing training
• Able to continue training throughout the study period
• Willing to voluntarily participate in the study
• Able to provide written and/or verbal informed consent

You may not qualify if:

• Presence of chronic diseases (e.g., diabetes, cardiovascular disorders)
• Any injury or musculoskeletal condition preventing continuation of training
• Known allergy or hypersensitivity to jackfruit or its components
• Use of medications or supplements that could interfere with study outcomes
• Individuals who refuse to provide informed consent

Sponsors & Collaborators

• Bayburt University: lead

Study Sites (1)

Bayburt Gençlik Merkezi Kapali Spor Salonu

Bayburt, Merkez, 69000, Turkey (Türkiye)

Location

Related Links

• This study investigates the effects of jackfruit consumption on adipokine levels (irisin, omentin-1), brain-derived neurotrophic factor (BDNF), cognitive performance, and anthropometric parameters in young boxers aged 18-25.

Study Officials

• BÜLENT BAYRAKTAR

  BAYBURT ÜNİVERSİTESİ

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Researcher / Principal Investigator/ Master's Student

Model Details: Participants were randomly assigned to four parallel groups (J0, J100, J200, J300) receiving different doses of jackfruit oil extract (0, 100, 200, 300 mg/kg). Each group received the assigned intervention for 30 days, and outcomes including salivary irisin, omentin-1, BDNF levels, cognitive performance, and anthropometric measurements were assessed at baseline and at the end of the intervention.

Study Record Dates

• First Submitted: August 26, 2025
• First Posted: December 8, 2025
• Study Start: January 7, 2025
• Primary Completion: February 10, 2025
• Study Completion: June 10, 2025
• Last Updated: December 8, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ANALYTIC CODE
• Time Frame: De-identified participant-level data and supporting documents will be available to other researchers starting after publication of the main study results and will remain accessible for 5 years following publication.
• Access Criteria: "Access to de-identified participant-level data and supporting documents will be granted to qualified researchers for legitimate scientific purposes. Researchers must submit a request detailing their research objectives and methods, obtain approval from the institutional ethics committee, and sign a data use agreement. Approved researchers will receive access to the specified datasets and supporting materials electronically.

Locations

TU (1)