NCT07390149

Brief Summary

The present study aims to investigate the acute effects of inspiratory muscle warm-up (IWU) on 1RM performance in professional natural bodybuilders. The hypothesis is that IWU will lead to an increase in the pressure-generating capacity of the inspiratory muscles, thereby resulting in improved 1RM strength performance. The anticipated findings are expected to contribute not only to the enhancement of maximal strength performance but also to the improvement of exercise efficiency through increased respiratory muscle endurance. It is submitted that these outcomes may ultimately provide insights into the long-term sustainability of professional athletes' performance. Twenty male athletes who had competed in national and international professional natural bodybuilding competitions were recruited for this study. The participants had an average experience in natural bodybuilding of 3.21 years, with a standard deviation of ± 1.44 years, and trained for more than five hours per week. The data collection period commenced in July 2025. The study was designed as a randomized controlled experimental trial. Participants were randomly assigned to two groups by a computerized program at three visits after the trial, based on their first measurement: inspiratory warm-up (IWU) group or control (CON) group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
27

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 5, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 15, 2025

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 5, 2026

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

January 18, 2026

Completed
18 days until next milestone

First Posted

Study publicly available on registry

February 5, 2026

Completed
Last Updated

May 7, 2026

Status Verified

May 1, 2026

Enrollment Period

3 months

First QC Date

January 18, 2026

Last Update Submit

May 1, 2026

Conditions

Keywords

acute interventionshuman physiologyinspiratory muscle warm-upexercise performancebodybuilders1RM

Outcome Measures

Primary Outcomes (2)

  • 1RM

    One-Repetition maximum (1RM) bench press performance

    Day 1

  • maximal inspiratory pressures (MIP )

    maximal inspiratory pressures (MIP )

    Day 1

Secondary Outcomes (5)

  • maximal expiratory pressures (MEP)

    Day 1

  • Forced vital capacity (FVC)

    Day 1

  • forced expiratory volume in one second (FEV1)

    Day 1

  • FEV1/FVC ratio (Tiffeneau index)

    Day 1

  • peak expiratory flow (PEF)

    Day 1

Study Arms (2)

IWU

OTHER

The IWU group performed both inspiratory muscle warm-up and standard exercise warm-up.

Other: IWUOther: Control

Control Group

OTHER

The CON group performed only the standard warm-up.

Other: IWUOther: Control

Interventions

IWUOTHER

The IWU group performed both inspiratory muscle warm-up and standard exercise warm-up.

Also known as: Inspiratory muscle warm-up
Control GroupIWU
ControlOTHER

The CON group performed only the standard warm-up.

Control GroupIWU

Eligibility Criteria

Age18 Years - 35 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsMale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • They were professional natural bodybuilders with less than three years of experience. ,
  • Male professional natural bodybuilders aged 18-35 years
  • Full participation in training and matches during the previous 6 months,
  • Ability to perform maximal exercise testing

You may not qualify if:

  • Individuals were deemed ineligible on the basis of a medical history that included any chronic or acute respiratory disease.
  • Individuals were considered ineligible if they were taking any prescription medication that could affect their response to exercise.
  • In accordance with the stipulated criteria, individuals were deemed to be ineligible for participation in the study if they had a history of current smoking or had smoked within the past year.
  • Individuals were considered ineligible for participation in the study if they had participated in similar studies within the previous six months.
  • Prior to participation, all individuals were required to sign a formal waiver, thereby affirming their adherence to the World Anti-Doping Agency Code.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gumushane Univetsity

Gümüşhane, Gümüşhane Province, (542) 442-7444, Turkey (Türkiye)

Location

Study Officials

  • Coşkun YILMAZ, associate professor

    Gümüşhane Üniversity

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Model Details: This study used a randomized, parallel-group design. Participants were randomly allocated to either the inspiratory warm-up (IWU) group or the control (CON) group. All participants completed baseline assessments prior to randomization and remained in their assigned group throughout the study. No crossover between conditions was implemented. Outcome measures were assessed across multiple visits to evaluate pre- and post-intervention responses within each group.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
ASSOC. PROF.

Study Record Dates

First Submitted

January 18, 2026

First Posted

February 5, 2026

Study Start

January 5, 2025

Primary Completion

April 15, 2025

Study Completion

January 5, 2026

Last Updated

May 7, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Individual participant data (IPD) will not be shared because the dataset consists of a small sample of elite athletes, and sharing de-identified data could still pose a risk of participant re-identification. In addition, no data-sharing agreement or participant consent for IPD sharing was established at the time of study design. Aggregate data supporting the findings are reported within the published article.

Locations