Trials Sponsors Conditions Drugs Pricing

Conditions

Acute Kidney Failure Acute Kidney Injury Hypothermic Circulatory Arrest Time Pulmonary Thromboembolisms

Keywords

AKIAcute Kıdney InjuryPTEPulmonary ThromboembolismsTCAHypothermic Circulatory Arrest Time

Outcome Measures

Primary Outcomes (1)

Incidence and Perioperative Determinants of Postoperative Acute Kidney Injury
The primary outcome is the occurrence of postoperative acute kidney injury (AKI) within 48 hours of surgery, defined according to KDIGO 2012 criteria using both serum creatinine changes from baseline and hourly urine output. AKI is analysed as a binary variable (yes/no) and further classified by severity stage (1, 2 or 3). Independent perioperative determinants of AKI - including extracorporeal circulation duration, deep hypothermic circulatory arrest duration, aortic cross-clamp time, age and early postoperative albumin - are assessed using multivariable logistic regression.
up to 48 hours, postoperatively

Secondary Outcomes (3)

Severity of Acute Kidney Injury According to KDIGO Staging
up to 48 hours, postoperatively

Eligibility Criteria

Age18 Years - 85 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

This study will include adult patients aged 18 to 85 years who underwent pulmonary endarterectomy at the Cardiothoracic Surgery Unit of Kosuyolu Kartal Heart Training and Research Hospital (Kosuyolu KHTRH), a single tertiary referral center in Istanbul, Turkey, between January 1, 2018, and December 31, 2020. Patients meeting the inclusion criteria will have complete perioperative data available, including total circulatory arrest duration and postoperative renal function parameters. Individuals younger than 18 years of age and pregnant women at the time of surgery will be excluded.

You may qualify if:

Sponsors & Collaborators

Ebru Girgin Dinc
Otherlead

Study Sites (1)

Kosuyolu Heart Training and Research Hospital

Istanbul, Kartal, 34846, Turkey (Türkiye)

MeSH Terms

Conditions

Acute Kidney InjuryPulmonary Embolism

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLung DiseasesRespiratory Tract DiseasesEmbolismEmbolism and ThrombosisVascular DiseasesCardiovascular Diseases

Study Officials

Atakan ERKILINC, MD, Associate Professor
University of Health Sciences, Kosuyolu Heart Training and Research Hospital, Kartal, ISTANBUL
PRINCIPAL INVESTIGATOR

Enrollment

150 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: M.D., Anesthesiologist

Study Record Dates

First Submitted

August 13, 2025

First Posted

August 20, 2025

Study Start

June 30, 2024

Actual (reported)

AKI After Pulmonary Endarterectomy

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations