NCT07127367

Brief Summary

The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons following stroke

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
5mo left

Started Sep 2025

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress63%
Sep 2025Oct 2026

First Submitted

Initial submission to the registry

August 11, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 17, 2025

Completed
15 days until next milestone

Study Start

First participant enrolled

September 1, 2025

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2026

Last Updated

August 17, 2025

Status Verified

August 1, 2025

Enrollment Period

1.1 years

First QC Date

August 11, 2025

Last Update Submit

August 11, 2025

Conditions

Keywords

MemoryLearningStroke

Outcome Measures

Primary Outcomes (2)

  • CVLT-III

    16 words from 4 semantic categories presented over 5 learning trials. Includes Free and cued immediate and delayed recall and delayed recognition

    baseline, week 7 and 6 months following intervention.

  • modified Ecological Memory Simulations (EMS)

    Everyday memory simulations, recalling a story or directions from a doctor

    Baseline, week 7, and 6 months following intervention

Study Arms (2)

KFmSMT

EXPERIMENTAL

Memory training on computer, 2 times per week for 5 weeks

Behavioral: Memory Training

Memory program

SHAM COMPARATOR

Memory training on computer, 2 times per week for 5 weeks

Behavioral: Memory Training

Interventions

Memory TrainingBEHAVIORAL

Memory retraining exercises will be administered on a laptop computer twice a week for five weeks (10 training sessions).

KFmSMTMemory program

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Stroke over 1 year ago
  • Memory challenges

You may not qualify if:

  • Aphasia
  • non English speaking

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kessler Foundation

East Hanover, New Jersey, 07936, United States

Location

Related Publications (2)

  • Berg I, Koning-Haanstra M, Deelman B. Long-term effects of memory rehabilitation: A controlled study. Neuropsychol Rehabil. 1(2):97-111.

    BACKGROUND
  • Gross AL, Rebok GW. Memory training and strategy use in older adults: results from the ACTIVE study. Psychol Aging. 2011 Sep;26(3):503-17. doi: 10.1037/a0022687.

    PMID: 21443356BACKGROUND

MeSH Terms

Conditions

Stroke

Interventions

Cognitive Training

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Neurological RehabilitationRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Nancy Chiaravalloti, PhD

    Kessler Foundation

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 11, 2025

First Posted

August 17, 2025

Study Start

September 1, 2025

Primary Completion (Estimated)

October 1, 2026

Study Completion (Estimated)

October 1, 2026

Last Updated

August 17, 2025

Record last verified: 2025-08

Locations