NCT07124780

Brief Summary

The purpose of this study is to compare two models of employment services for people with obsessive-compulsive disorder (OCD) interested in finding and maintaining employment. All 40 participants will receive up to 12 sessions of the first-line treatment for OCD called exposure and response prevention, a form of Cognitive Behavioral Therapy (CBT). Assigned by chance, half of the people will also receive Individual Placement and Support (IPS); the other half will receive standard vocational services (SVS). This study will compare these two approaches for helping adults with OCD find and maintain work.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
15mo left

Started Apr 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress3%
Apr 2026Aug 2027

First Submitted

Initial submission to the registry

August 4, 2025

Completed
11 days until next milestone

First Posted

Study publicly available on registry

August 15, 2025

Completed
8 months until next milestone

Study Start

First participant enrolled

April 1, 2026

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2027

Expected
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2027

Last Updated

March 3, 2026

Status Verified

March 1, 2026

Enrollment Period

1 year

First QC Date

August 4, 2025

Last Update Submit

March 2, 2026

Conditions

Keywords

supported employmentobsessive-compulsive disorder

Outcome Measures

Primary Outcomes (2)

  • Competitive employment

    Employed at least one work shift in an integrated work setting in the open job market at prevailing wages with supervision provided by personnel employed by the business.

    From enrollment to the end of 12 months

  • Hours worked

    Total hours of competitive employment

    From enrollment to the end of 12 months

Secondary Outcomes (2)

  • Yale-Brown Obsessive Compulsive Scale (scores range from 0-40 with higher scores indicating greater OCD severity)

    From enrollment to the end of 12 months

  • Quality of Life Enjoyment and Satisfaction Scale (scores range from 14-70 with higher scores indicating greater life satisfaction and enjoyment)

    From enrollment to the end of 12 months

Study Arms (2)

Standard Vocational Services plus Cognitive Behavioral Therapy for OCD

ACTIVE COMPARATOR

Standard vocational services includes support in finding employment with support from the American Jobs Center over 12 months. Cognitive Behavior Therapy for OCD consists of a standard course of exposure and response prevention over 12 weeks, followed by monthly maintenance sessions for 12 months.

Behavioral: Standard Vocational Services

Individual Placement and Support plus Cognitive Behavior Therapy for OCD

EXPERIMENTAL

Individual Placement and Support includes support in finding employment with support from an IPS employment specialist over 12 months. Cognitive Behavior Therapy for OCD consists of a standard course of exposure and response prevention over 12 weeks, followed by monthly maintenance sessions for 12 months.

Behavioral: Individual Placement and Support (IPS)

Interventions

Individual Placement and Support is an evidence-based model of supported employment for individuals with mental illness. In IPS, participants will meet with an IPS specialist weekly who will help the study participant create resumes, conduct job searches online or in the community, complete job applications, role-play interviews, and, if requested, accompany them when visiting prospective employers.

Also known as: IPS
Individual Placement and Support plus Cognitive Behavior Therapy for OCD

In Standard Vocational Services, participants will meet with a representative from the American Jobs Center (AJC) who will help them find a job by identifying their interests, assess their skills and abilities, and advise them on in-demand jobs and potential training opportunities.

Also known as: SVS
Standard Vocational Services plus Cognitive Behavioral Therapy for OCD

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Primary diagnosis of OCD
  • Currently unemployed and interested in finding competitive employment
  • For those currently on medication: On a stable dose of psychiatric medication and willing to remain on this dose for the duration of CBT

You may not qualify if:

  • Currently receiving supported employment services
  • Active suicidality or recent suicide attempt
  • Active substance use problem (other than nicotine) that warrants treatment
  • Comorbid psychiatric conditions that significantly elevate the risk of study participation
  • Reside outside of New York State

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Interventions

Palliative Care

Condition Hierarchy (Ancestors)

Anxiety DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Sapana R Patel, Ph.D.

    The New York State Psychiatric Institute

    PRINCIPAL INVESTIGATOR
  • Blair Simpson, MD, Ph.D.

    The New York State Psychiatric Institute

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sapana R. Patel, Ph.D.

CONTACT

Blair Simpson, M.D., Ph.D.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Medical Psychology

Study Record Dates

First Submitted

August 4, 2025

First Posted

August 15, 2025

Study Start

April 1, 2026

Primary Completion (Estimated)

April 1, 2027

Study Completion (Estimated)

August 1, 2027

Last Updated

March 3, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share