iCBT for Adult Obsessive-Compulsive Disorder

NCT07081438 | Not Yet Recruiting

• 1 other identifier: HCB/2023/0643
• Study Type: interventional
• Target: 25
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of the study is to assess the feasibility, acceptability, and potential effects of therapist-guided internet-delivered cognitive-behavior therapy (iCBT) for adult obsessive-compulsive disorder, using a recently developed digital platform.

Conditions

Obsessive-Compulsive Disorder (OCD)

Keywords

Obsessive-Compulsive Disorder; Cognitive-behavior therapy; icbt; Online treatment; e-health

Outcome Measures

Primary Outcomes (1)

• Feasibility (recruitment and retention rates and therapist burden)

  The investigators will assess feasibility by recording recruitment rates, retention rates, and therapist burden (time spent by the therapist sending emails, reviewing materials, etc.).

  From enrollment to the end of treatment at 12 weeks

Other Outcomes (6)

• Acceptability (Treatment Acceptability/Adherence Scale, TAAS)

  Immediately after the intervention

• Yale-Brown Obsessive-Compulsive Scale

  Baseline and 12 weeks

• Clinical Global Impression (CGI)-Severity

  Baseline and 12 weeks

Study Arms (1)

Internet-delivered Cognitive Behavioral Therapy (iCBT)

EXPERIMENTAL

Behavioral: icbt

Interventions

icbt BEHAVIORAL

12-Week Therapist-Based iCBT for OCD (Adapted Version of OCD Net: https://therapistguide.webcbt.se/index.html)

Internet-delivered Cognitive Behavioral Therapy (iCBT)

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age between 18 and 75
• Internet access
• Principal diagnosis of OCD, based on DSM-5
• Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) Total Severity Score \> 16
• Ability to communicate in Spanish
• For participants taking psychotropic medication for OCD: at least eight weeks on stable medication and willingness to stay on the same medication/doses for the 12 weeks of the study

You may not qualify if:

• Estimated IQ \< 70, as per the Vocabulary subtest of the Wechsler Adults Intelligence Scale for Children (WISC)
• Eight or more previous sessions of CBT for OCD with an experienced therapist during the last 12 months
• Ongoing psychological treatment for OCD
• Diagnosis of organic brain disorder, intellectual disability, autism spectrum disorder, psychosis, bipolar disorder, low-weight anorexia nervosa, or alcohol/substance dependence
• Immediate risk to self or others (e.g., suicidality)
• Inability to communicate in Spanish
• Low motivation to participate (i.e., the patient does not believe the therapy will be helpful at all)
• Insufficient time to work on the treatment (about 30 minutes per day)

Sponsors & Collaborators

• Hospital Clinic of Barcelona: lead

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Condition Hierarchy (Ancestors)

Anxiety Disorders; Mental Disorders

Study Officials

• Joaquim Radua, MD

  Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS)

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Miquel A Fullana, PhD

CONTACT

34+637908990; mafullana@clinic.cat

Maria Sagué, MD

CONTACT

34 +932 27 54 00; msague@clinic.cat

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Single-Group Assignment

Study Record Dates

• First Submitted: July 10, 2025
• First Posted: July 23, 2025
• Study Start: September 1, 2025
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): March 1, 2027
• Last Updated: July 31, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share