NCT06647589

Brief Summary

The purpose of the study is to examine the effects and feasibility of a specific form of psychotherapy, acceptance and commitment therapy (ACT), on religiously oriented obsessive and compulsive disorder (OCD).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
2mo left

Started Jul 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress80%
Jul 2025Sep 2026

First Submitted

Initial submission to the registry

October 16, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 18, 2024

Completed
10 months until next milestone

Study Start

First participant enrolled

July 30, 2025

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Last Updated

March 19, 2026

Status Verified

March 1, 2026

Enrollment Period

1.1 years

First QC Date

October 16, 2024

Last Update Submit

March 17, 2026

Conditions

Keywords

scrupulosityreligionacceptance and commitment therapyobsessive-compulsive disorderOCD

Outcome Measures

Primary Outcomes (2)

  • Scrupulosity Obsessions and Compulsions Scale

    The Scrupulosity Obsessions and Compulsions Scale (SOCS) is a 10-item scale that asks participants how often they experience religious OCD obsessions and compulsions. The questions are asked on a scale ranging from 0 (Very Rarely) to 5 (Very Often).

    At baseline, 4 weeks, 8 weeks, and post-intervention (12 weeks)

  • Experiential Avoidance Rating Scale

    The Experiential Avoidance Rating Scale (EARS) is a 6-item scale that asks participants how true statements about avoiding experiences are for them. The questions are asked on a scale ranging from 1 (Never True) to 5 (Very Often True).

    At baseline, 4 weeks, 8 weeks, and post-intervention (12 weeks)

Secondary Outcomes (9)

  • Centrality of Religiosity Scale - Interreligious 20

    Pre and post intervention which in general lasts 12 weeks

  • Yale-Brown Obsessive and Compulsive Scale - Self Report

    Pre and post intervention which in general lasts 12 weeks

  • Patient Health Questionnaire - 9

    Pre and post intervention which in general lasts 12 weeks

  • Generalized Anxiety Disorder - 7

    Pre and post intervention which in general lasts 12 weeks

  • The Intrinsic Spirituality Scale

    Pre and post intervention which in general lasts 12 weeks

  • +4 more secondary outcomes

Study Arms (1)

Acceptance and Commitment Therapy

EXPERIMENTAL

Participants will receive twelve consecutive weeks of acceptance and commitment therapy

Behavioral: Acceptance and Commitment Therapy

Interventions

participants will then receive ACT-based individual therapy weekly for twelve weeks.

Acceptance and Commitment Therapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years old
  • Meet cutoff scores for scrupulosity

You may not qualify if:

  • Presence of psychotic symptoms within six months of screening
  • Current suicidal/homicidal plan/intent and/or a suicide/homicide attempt within 6 months of screening
  • Non-suicidal self-injury within 6 months of screening
  • Narcotics use within 3 months of screening
  • Purging/restricting behavior within 3 months of screening.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Alabama at Birmingham

Birmingham, Alabama, 35233, United States

RECRUITING

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Interventions

Acceptance and Commitment Therapy

Condition Hierarchy (Ancestors)

Anxiety DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Cognitive Behavioral TherapyBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Central Study Contacts

David Johnson

CONTACT

Nicholas Borgogna, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Graduate Student

Study Record Dates

First Submitted

October 16, 2024

First Posted

October 18, 2024

Study Start

July 30, 2025

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

March 19, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

Locations