Response of Lipid Profile to Virtual Reality Games Versus Moderate Aerobic Exercise Training in Children With Obesity

NCT07073651 | Completed

• 1 other identifier: IRB00014233-8
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 2

Brief Summary

This trial is aiming to study the effect of virtual reality video gaming in comparison with moderate intensity aerobic exercises on lipid profile in children with Obesity

Conditions

Obese Children and Adolescents; Adolescent Obesity; Obesity; Body Mass Index

Keywords

Obesity; Body mass index; Virtual Reality games; aerobic exercise; adolescent obesity; obese children; Moderate intensity aerobic exercise; dietary advices

Outcome Measures

Primary Outcomes (5)

• Body mass index

  It is the weight (in kilograms) divided by the height (in meter squares)

  From enrollment to the end of treatment at 12 weeks

• Serum triglycerides

  Level of triglycerides fats in blood in measured in laboratory using venous blood sample

  From enrollment to the end of treatment at 12 weeks

• Total Cholesterol

  Level of total cholesterol in blood in measured in laboratory using venous blood sample

  From enrollment to the end of treatment at 12 weeks

• High Density Lipoproteins (HDL)

  High Density Lipoproteins (HDL) cholesterol fats are measured in laboratory using a venous blood sample

  From enrollment to the end of treatment at 12 weeks

• Low Density Lipoproteins (LDL)

  Low Density Lipoproteins (LDL) cholesterol fats are measured in laboratory using a venous blood sample

  From enrollment to the end of treatment at 12 weeks

Secondary Outcomes (1)

• HDL ratio

  From enrollment to the end of treatment at 12 weeks

Study Arms (2)

Virtual Reality Exercise

EXPERIMENTAL

The experimental group included 60 adolescent obese children of both genders (class I obesity, BMI: 30-34.99) who received diet advices and virtual reality exercises 5 times per week for 12 weeks. Each participating child started the session with 5 minutes warming up exercises then followed by the main part which was consisted of 30 min of exercise where the child played the game using virtual reality X-Box and did different physical activities that included both the upper and lower extremities according to the game's requirements, and after that a 5 min cool-down part that involved some static flexibility exercise to allow the heart rate to lower, the total session that would be applied about 40 min (including 30 mins of Virtual reality exercises)

Other: Dietary Advices; Other: Virtual reality games exercise

Moderate intensity aerobic exercise

ACTIVE COMPARATOR

This group serves as the control group, it included 60 adolescent obese children of both genders (class I obesity, BMI: 30-34.99) who received diet advice and moderate intensity aerobic exercises (using treadmill training) 5 times per week for 12 weeks. Each participating child started the session with 5 minutes of warming-up exercises. Then the main exercise phase is performed at 50-60% of age-predicted peak heart rate using a treadmill for 30 minutes. Finally, a 5 min cool-down period is allowed, the total session took 40 minutes.

Other: Moderate Intensity Aerobic Exercise; Other: Dietary Advices

Interventions

Moderate Intensity Aerobic Exercise OTHER

moderate intensity aerobic exercises (using treadmill training) 5 times per week for 12 weeks. Each participating child started the session with 5 minutes of warming-up exercises. Then the main exercise phase is performed at 50-60% of age-predicted peak heart rate using a treadmill for 30 minutes. Finally, a 5 min cool-down period is allowed, the total session took 40 minutes.

Moderate intensity aerobic exercise

Dietary Advices OTHER

The Obese adolescent children participated in the study received diet advices based on a balanced low calorie diet (1500 Kcal)

Moderate intensity aerobic exercise; Virtual Reality Exercise

Virtual reality games exercise OTHER

Virtual reality games exercises 5 times per week for 12 weeks. Each participating child started the session with 5 minutes warming up exercises then followed by the main part which was consisted of 30 min of exercise where the child played the game using virtual reality X-Box and did different physical activities that included both the upper and lower extremities according to the game's requirements, and after that a 5 min cool-down part that involved some static flexibility exercises to allow the heart rate to lower, the total session that would be applied about 40 min (including 30 mins of Virtual reality exercises)

Virtual Reality Exercise

Eligibility Criteria

• Age: 11 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Obese adolescent children
• age from 11 to 18 years old only.
• Class I Obesity (Body Mass Index from 30 to 34.99 kg/m2)
• Clinically and medically stable
• Without any impairment of sensation or other neurological or psychological problems.

You may not qualify if:

• Adolescents with visual and/or auditory defects
• Normal weight adolescent children (Body Mass Index from 18 to 24.99 kg/m2) or below average weight (BMI less than 18 kg/m2) or Class II and III Obesity (BMI above 35 kg/m2)
• Children with significant tightness and/or deformity of upper or lower limbs
• Participants with neurological disorders that affect balance or mentality (e.g. epilepsy).
• Adolescents with advanced radiographic changes include: Bone destruction, Bony ankylosis, Knee joint subluxation, and Epiphysial fracture)
• Any lower limb deformities in the lower limbs.
• Participants with cardiopulmonary diseases.
• Diabetic children or those under insulin therapy, uncontrolled bronchial asthma, anemia, and Pathological causes of obesity (endocrinal, genetic syndromes...etc.).

Sponsors & Collaborators

• Badr University: lead

Study Sites (2)

Badr University in Cairo faculty of physical therapy

Cairo, Egypt

Location

El-Mahaba Specialized Charity Polyclinics.

Cairo, Egypt

Location

MeSH Terms

Conditions

Pediatric Obesity; Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Radwa S Abdulrahman, PhD

  Ass. Prof. Dept. of PT for Pediatric, Faculty of Physical Therapy, Badr University in Cairo, Egypt.

  PRINCIPAL INVESTIGATOR

• Hayam M Mahmoud, PhD

  Professor Dept. of PT for Neurology & Neurosurgery, Faculty of Physical Therapy, Cairo Univ. Egypt

  STUDY CHAIR

• Wael OA Abd El-Khalek, PhD

  Lecturer, Dept. of Basic Sciences, Faculty of Physical Therapy, Badr University in Cairo, Egypt.

  STUDY CHAIR

• Noha A Fouad, PhD

  Ass Prof Dept. of PT for Women's Health Faculty of Physical Therapy Badr University in Cairo, Egyp

  STUDY CHAIR

• Mina AG Elias, PhD

  Department of Physical Therapy Ahmed Maher Teaching hospital, General Organization For Teaching Hospitals And Institutes (GOTHI)

  PRINCIPAL INVESTIGATOR

• Ashraf H Saleh, PhD

  Prof Dept. of PT for Surgery and Burn, Faculty of Physical Therapy Badr University in Cairo, Egyp

  STUDY CHAIR

• Mona M Abdelkhalek, PhD

  Ass. Prof. Dept. of PT for Internal Medicine, Faculty of Physical Therapy, Badr University in Cairo, Egypt.

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: July 10, 2025
• First Posted: July 18, 2025
• Study Start: July 10, 2024
• Primary Completion: May 31, 2025
• Study Completion: June 30, 2025
• Last Updated: July 18, 2025

Record last verified: 2025-07

Locations

EG (2)