Effect of HIIT Vs Moderate Intensity Aerobic Exercise on Insulin Resistance in Type 2 DM

NCT05902546 | Completed

• 1 other identifier: BUC-IACUC-230507-21
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 4

Brief Summary

Comparing between the efficacy of high intensity interval training and moderate intensity aerobic exercises on insulin resistance in type 2 Diabetes Mellitus.

Conditions

Diabetes Mellitus; Insulin Resistance

Outcome Measures

Primary Outcomes (1)

• Insulin Resistance (Homa-IR)

  Serum insulin resistance indicator (Homa-IR)

  1 month

Study Arms (2)

High intensity interval training (group A)

EXPERIMENTAL

30 Diabetic patients (Type 2 Diabetes Mellitus) will receive high intensity interval training

Other: High intensity interval training

moderate intensity aerobic exercise (group B)

EXPERIMENTAL

30 Diabetic patients (Type 2 Diabetes Mellitus) will receive moderate intensity aerobic exercise

Other: moderate intensity aerobic exercise

Interventions

High intensity interval training OTHER

Patients will receive interval training exercise of high intensity. This includes several rounds that alternate between several minutes of high intensity movements to significantly increase the heart rate to at least 80% of one's maximum heart rate, followed by short periods of rest

High intensity interval training (group A)

moderate intensity aerobic exercise OTHER

Patients will receive moderate intensity continuous aerobic exercise (walking) for 40 minutes (preceded by 10 minutes warming up and followed by 5 minutes cooling down)

moderate intensity aerobic exercise (group B)

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Type 2 Diabetes Mellitus Patients.
• Diagnosed for more than 1 years at the time of the study.
• Patients with fair control of blood glucose using hypoglycemic drugs

You may not qualify if:

• Type 1 (Insulin Dependant) Diabetes Mellitus patients.
• Patients with disability that can't perform exercises.
• Patient with known Cardiovascular diseases.
• Patients with kidney/liver diseases

Sponsors & Collaborators

• Badr University: lead
• Ahmed Maher Teaching Hospital: collaborator

Study Sites (4)

Ahmed Maher Teaching Hospital

Cairo, 11662, Egypt

Location

Elamahaba Specialized Charity Polyclinics

Cairo, 11725, Egypt

Location

Trust Physical Therapy Center and Rehabilitation

Cairo, 11771, Egypt

Location

Badr University in Cairo, Faculty of Physical Therapy, Outpatient Clinic

Cairo, 11829, Egypt

Location

MeSH Terms

Conditions

Diabetes Mellitus; Insulin Resistance

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Hyperinsulinism

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Mina AG Elias, Dr.

  Dept of Internal Medicine & geriatric, Faculty of Physical Therapy, Badr University in Cairo, Egypt.

  PRINCIPAL INVESTIGATOR

• Khaled M Mounir, Dr.

  Dept of Cardiopulmonary & internal medicine rehab, Faculty of Physical Therapy, Galala Univ; Egypt.

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer Internal Medicine & Geriatrics, Faculty of Physical Therapy, Badr University in Cairo.

Study Record Dates

• First Submitted: June 3, 2023
• First Posted: June 15, 2023
• Study Start: January 7, 2023
• Primary Completion: August 31, 2023
• Study Completion: September 30, 2023
• Last Updated: October 27, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

EG (4)