Effects of Smoking Addiction on Lower Limb Speed and Coordination

NCT07061522 | Recruiting

• 1 other identifier: Smoking Add-Coordination-1
• Study Type: observational
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

This observational case-control study will investigate the impact of smoking addiction on lower extremity speed and coordination in young adults. Participants aged 18-25 will be divided into two groups based on their smoking status. The study will compare motor coordination and sprint performance between smokers and non-smokers using objective physical tests under standardized laboratory conditions.

Conditions

Smoking Cessation

Outcome Measures

Primary Outcomes (2)

• Lower Extremity Coordination Score

  Tool: LEMOCOT (Lower Extremity Motor Coordination Test) Description: Total number of valid taps within 20 seconds.

  Baseline

• Sprint Time

  Tool: 30-Meter Sprint Test Description: Time in seconds taken to complete a 30-meter run at maximum speed.

  Baseline

Secondary Outcomes (3)

• Nicotine Dependence Score

  Baseline

• BMI (Body Mass Index)

  Baseline

• Bimalleolar Diameter and Circumference

  Baseline

Study Arms (2)

Smoking Addiction Group

Participants in this group will be individuals who meet the criteria for smoking addiction based on both the DSM-IV-TR criteria and the Fagerström Test for Nicotine Dependence. They must have smoked at least one cigarette per day for the past 12 months.

Other: Behavioral/Physical Assessment

Non-Smokers

Participants in this group will be healthy individuals aged 18-25 with no history of smoking within the past year. They will be matched in terms of age and BMI to the smoking group and will serve as the control cohort.

Other: Behavioral/Physical Assessment

Interventions

Behavioral/Physical Assessment OTHER

This study will not include any therapeutic or clinical intervention. Instead, participants will undergo a series of structured physical and questionnaire-based assessments to evaluate lower extremity motor performance. These include the Fagerström Test for Nicotine Dependence and DSM-IV-TR criteria to classify smoking addiction. Anthropometric measurements such as Body Mass Index (BMI) and bimalleolar diameter/circumference will be recorded to assess potential confounding structural factors. Lower extremity coordination will be evaluated using the Lower Extremity Motor Coordination Test (LEMOCOT), and movement speed will be assessed with a 30-meter sprint test. All assessments will be conducted once in a controlled laboratory setting and are intended solely for comparative analysis between smokers and non-smokers.

Non-Smokers; Smoking Addiction Group

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Healthy young adults aged 18-25 who are either current smokers (according to DSM-IV-TR criteria) or non-smokers. Participants must be physically active enough to perform sprint and coordination tasks, with BMI within a defined range (18.5-29.9 kg/m²). Participants are recruited from a university setting using both institutional announcements and snowball sampling.

You may qualify if:

• Smoking ≥1 cigarette daily for at least 12 months
• Age between 18-25
• Literate and cooperative
• BMI: 18.5-29.9 kg/m²

You may not qualify if:

• Orthopedic, neurological, or neuromuscular conditions impairing walking
• Chronic pulmonary or cardiac disease
• Cognitive impairment
• BMI ≥30 kg/m²

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead

Study Sites (1)

Esra Pehlivan

Istanbul, Üsküdar, 34668, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Smoking Cessation

Interventions

Restraint, Physical

Condition Hierarchy (Ancestors)

Health Behavior; Behavior

Intervention Hierarchy (Ancestors)

Behavior Control; Therapeutics; Immobilization; Investigative Techniques

Central Study Contacts

Esra Pehlivan, Associate Professor

CONTACT

+90216 777 87 77; esra.pehlivan@sbu.edu.tr

Edanur Kocakaplan

CONTACT

2103006006@ogrenci.sbu.edu.tr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: July 11, 2025
• Study Start: August 26, 2025
• Primary Completion (Estimated): July 20, 2026
• Study Completion (Estimated): July 20, 2026
• Last Updated: August 27, 2025

Record last verified: 2025-08

Locations

TU (1)