Pharmacist Intervention to Improve Smoking Cessation

NCT06943287 | Active Not Recruiting

• 1 other identifier: 202411248
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to assess the effectiveness of a remote pharmacist intervention to help smokers quit. The main questions it aims to answer are:

• Will smokers being screened for lung cancer with low-radiation-level chest computed tomography (CT) be willing to participate in this study and talk to the pharmacist about smoking cessation?
• Will those in the intervention group be more likely to report smoking cessation than those in the control group. Participants in the intervention group will be asked to complete a baseline survey; speak with a pharmacist via phone call at baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 10 weeks, and 12 weeks; and complete an exit survey. Participants in the control group will be asked to complete a baseline survey and an exit survey.

Conditions

Smoking Cessation

Outcome Measures

Primary Outcomes (1)

• Number of Interactions with Pharmacist

  The number of phone calls the intervention participants complete with the research pharmacist.

  12 weeks

Secondary Outcomes (3)

• Number of Nicotine Replacement Therapies Used to Quit Smoking

  12 weeks

• Number of Non-Medication Tool Used to Quit Smoking

  12 weeks

• Number of Successful Quit Attempts

  12 weeks

Study Arms (2)

Pharmacist Intervention Group

EXPERIMENTAL

Behavioral: Pharmacist Intervention

Control Group

NO INTERVENTION

Interventions

Pharmacist Intervention BEHAVIORAL

If the patient is randomized to the intervention group, they will complete a series of phone calls with the research pharmacist. These will occur at baseline (within 1 to 2 days of enrollment), 2-weeks, 4-weeks, 6-weeks, 8-weeks, 10-weeks, and 12-weeks. During these calls, the research pharmacist will ask the patient about any past quit attempts; when they had their last cigarette; if they have been prescribed any cessation medications; if they have picked up their medication; if they have started the medication; they will assess their stage of change for quitting; discuss pros, cons, and barriers of quitting; behavioral responses to triggers/urges; and make any necessary nicotine replacement therapy (NRT; i.e., nicotine patches, gums, lozenges, inhalers, and/or nasal sprays) changes. Each call is expected to take 20-30 minutes.

Pharmacist Intervention Group

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Current smoker
• Current patient in the Lung Cancer Screening Program

You may not qualify if:

• Unable to speak/read English
• Unable to provide their own written informed consent

Sponsors & Collaborators

• University of Iowa: lead

Study Sites (1)

University of Iowa Health Care

Iowa City, Iowa, 52242, United States

Location

MeSH Terms

Conditions

Smoking Cessation

Condition Hierarchy (Ancestors)

Health Behavior; Behavior

Study Officials

• Jacob E Simmering, PhD

  University of Iowa

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 16, 2025
• First Posted: April 24, 2025
• Study Start: August 11, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: April 17, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)