NCT07075068

Brief Summary

This observational study will aim to investigate the effects of cigarette addiction on lower extremity motor coordination and movement speed in young adults. The study will include healthy participants aged 18-25 years, divided into smokers and non-smokers. Motor coordination will be assessed using the Lower Extremity Motor Coordination Test (LEMOCOT), and speed will be evaluated with a 30-meter sprint test. Nicotine dependence will be evaluated in smokers using the Fagerström Test. The findings will provide insight into the possible functional impacts of nicotine addiction on motor performance.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for all trials

Timeline
3mo left

Started Jul 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress80%
Jul 2025Jul 2026

First Submitted

Initial submission to the registry

July 10, 2025

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 20, 2025

Completed
9 days until next milestone

Study Start

First participant enrolled

July 29, 2025

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2026

Last Updated

July 30, 2025

Status Verified

July 1, 2025

Enrollment Period

12 months

First QC Date

July 10, 2025

Last Update Submit

July 29, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • LEMOCOT Score (Lower Extremity Motor Coordination Test)

    The number of correct taps within 20 seconds will be measured for each participant.

    Baseline

  • 30-Meter Sprint Time

    Time (in seconds) required to complete a 30-meter sprint will be recorded and averaged from two trials.

    Baseline

Secondary Outcomes (3)

  • Fagerström Test for Nicotine Dependence Score

    Baseline

  • Body Mass Index (BMI)

    Baseline

  • Bimalleolar Circumference and Diameter Measurement

    Baseline

Study Arms (2)

Smokers

Individuals who will meet WHO and DSM-IV-TR criteria for cigarette dependence.

Diagnostic Test: Behavioral and Functional Performance Assessment Battery

Non-Smokers

Individuals who will report no smoking behavior in the past year.

Diagnostic Test: Behavioral and Functional Performance Assessment Battery

Interventions

This study will include only observational functional assessments. No active intervention will be performed.This observational protocol will involve standardized assessments of lower extremity coordination (LEMOCOT), movement speed (30-meter sprint), and smoking-related behavioral patterns (Fagerström Test for Nicotine Dependence). These tools will be used to evaluate the potential impact of cigarette addiction on physical performance in young adults. No therapeutic or pharmacological intervention will be applied.

Non-SmokersSmokers

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

The study population will consist of healthy young adults aged between 18 and 25 years. A total of 24 participants will be included, with 12 individuals who meet the criteria for cigarette dependence and 12 who do not smoke. Participants will be recruited from a university setting using convenience and snowball sampling methods. All participants will be required to be cooperative, literate, and able to walk independently. They will also be screened to ensure a body mass index (BMI) between 18.5 and 29.9 kg/m². Smokers will be identified based on the World Health Organization (WHO) definition and the DSM-IV-TR diagnostic criteria. Individuals with orthopedic, neurologic, cardiopulmonary, or cognitive impairments will be excluded.

You may qualify if:

  • Age between 18 and 25 years
  • Able to walk independently
  • Literate and cooperative
  • Willing to participate voluntarily
  • BMI between 18.5 and 29.9 kg/m²
  • Daily smoking for at least one year based on WHO and DSM-IV-TR definitions

You may not qualify if:

  • Orthopedic, neurologic, or neuromuscular disorders affecting gait
  • Chronic cardiopulmonary disease
  • Cognitive impairments
  • Obesity (BMI ≥ 30 kg/m²)
  • History of acute cardiovascular events
  • Chronic heart failure or lung diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Esra Pehlivan

Istanbul, Üsküdar, 34668, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Smoking Cessation

Condition Hierarchy (Ancestors)

Health BehaviorBehavior

Central Study Contacts

Edanur Kocakaplan

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 10, 2025

First Posted

July 20, 2025

Study Start

July 29, 2025

Primary Completion (Estimated)

July 20, 2026

Study Completion (Estimated)

July 20, 2026

Last Updated

July 30, 2025

Record last verified: 2025-07

Locations