We Have Two Groups. Both Groups Received a Deep Serratus Anterior Plane Block. One Group Had a Catheter for Continuous Infusion, While the Other Received IV Analgesics Postoperatively. Analgesic Effects Between the Two Groups Were Compared

NCT07053397 | Completed

• 1 other identifier: SAP001
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this observational study is to compare the analgesic efficacy of continuous infusion via peripheral catheter versus single-shot serratus anterior plane block in women aged 18 to 80 undergoing breast-conserving surgery. The main questions it aims to answer are: Does continuous serratus anterior plane block via peripheral catheter provide superior postoperative analgesic efficacy compared to single-shot serratus anterior plane block? Second question is: Does continuous infusion via catheter in peripheral nerve blocks reduce the amount of intravenous analgesics consumed and improve patient comfort?

Conditions

Pain Management After Surgery; Regional Anaesthesia

Keywords

SAP; Deep SAP Block; Regional block; Peripheral block; Peripheral block cathather; continuous infusion via peripheral block cathather

Outcome Measures

Primary Outcomes (1)

• Numeric Rating Scale

  1 - 10 1 is minimum pain 10 is maximum pain the lower scale is better for pain management.

  Until discharge after surgery, during an average hospital stay of approximately 24 hours.

Study Arms (2)

SAPB

ACTIVE COMPARATOR

The SAPB arm receives single shot deep serratus anterior plane block before surgery. Also receives iv analgesic treatment after post-operative duration.

Procedure: Serratus Anterior Plane Block (SAPB) group

DSAPB

EXPERIMENTAL

The DSAPB arm receives deep serratus anterior plane block and cathather replacement before surgery. After surgery, the arm takes continous analgesic treatment via periferic block cathather.

Procedure: Serratus Anterior Plane Block (SAPB) group; Procedure: DSAPB

Interventions

Serratus Anterior Plane Block (SAPB) group PROCEDURE

The SAP block, which is among the chest wall blocks, provides its effect by blocking the lateral cutaneous branches of the T2-T9 intercostal nerves, n. intercostobrachial , n. longus thoracicus , n. thoracodorsal. SAP block can be performed in two ways: superficial and deep. The deep SAP block is administered between the serratus anterior and intercostal muscles, at the intersection point of the anterior axillary line and the level of the nipple (at the level of the 4th-5th ribs). It has a wide range of use for postoperative pain management in trauma surgery, cardiac surgery, thoracic surgery and breast surgery.

Also known as: serratus anterior plane block

DSAPB; SAPB

DSAPB PROCEDURE

The SAP block, which is among the chest wall blocks, provides its effect by blocking the lateral cutaneous branches of the T2-T9 intercostal nerves, n. intercostobrachial , n. longus thoracicus , n. thoracodorsal. SAP block can be performed in two ways: superficial and deep. The deep SAP block is administered between the serratus anterior and intercostal muscles, at the intersection point of the anterior axillary line and the level of the nipple (at the level of the 4th-5th ribs). Following hydrodissection between the serratus anterior and intercostal muscles, a single-shot injection is administered. Subsequently, a peripheral nerve block catheter is placed in the same region under ultrasound guidance.

Also known as: serratus anterior plane peripheral block cathather replacement

DSAPB

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Female patients aged 18 to 80 years
• Scheduled for breast-conserving surgery
• Classified as American Society of Anesthesiologists (ASA) physical status I, II, or III

You may not qualify if:

• Patients with coagulopathy
• Patients with wounds or infections at the block site
• Patients with known allergy to local anesthetic agents
• Patients with mental retardation or limited cooperation
• Patients who do not consent to participate in the study
• Patients who, for any reason, discontinue participation during the course of the study

Sponsors & Collaborators

• Istanbul Medeniyet University: lead

Study Sites (1)

Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi

Istanbul, Kadıköy, 34722, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Saposins; Population Groups

Intervention Hierarchy (Ancestors)

Sphingolipid Activator Proteins; Coenzymes; Enzymes and Coenzymes; Demography; Population Characteristics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: June 27, 2025
• First Posted: July 8, 2025
• Study Start: January 26, 2025
• Primary Completion: April 26, 2025
• Study Completion: May 26, 2025
• Last Updated: July 10, 2025

Record last verified: 2025-07

Locations

TU (1)