Open TAP-block in Pediatric Abdominal Surgery

NCT07352683 | Recruiting

• 1 other identifier: NOR001
• Study Type: interventional
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this trial is to evaluate an open TAP-block vs continuous administration of local anestetic via a wound catheter for postoperative pain management in patients 1-15 years of age undergoing open abdominal surgery.

Conditions

Pain Management After Surgery

Keywords

pediatric; TAP-block; postoperative pain management

Outcome Measures

Primary Outcomes (1)

• Postoperative opiates

  Amount of postoperative opiates administered

  during the first 24 hours following surgery and total opioids until discarge up to 14 days postoperative

Secondary Outcomes (2)

• Lenght of stay

  Days from surgery through study completeion, an average expected time of7 days

• Pain assessment

  End of surgery until 24 hours post-op

Study Arms (2)

TAP-block

EXPERIMENTAL

Subjects in the TAP-block arm will recieve an open TAP-block at the end of the procedure vbefore wound closure

Procedure: TAP-block

Wound infiltration

ACTIVE COMPARATOR

Subjects in the wound infiltration group will recieve contionious administration of local anastethic via a wound catheter placed subcutaneousley during wound closure.

Procedure: Wound catheter

Interventions

TAP-block PROCEDURE

Open TAP(transverse abdominal plane)-block placed by the surgeon using open technique at end of surgery before wound closure

TAP-block

Wound catheter PROCEDURE

A catheter placed subcutainiousley for the continuous administration of local anestethic in the wound for up to 3 days post-op

Wound infiltration

Eligibility Criteria

• Age: 1 Year - 15 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Age 1-15 years
• Scheduled for elective or acute open adominal surgical procedure

You may not qualify if:

• chronic abdominal pain
• known allergy to local analgetic
• Stage 4 renal failure
• psychiatric ailnment

Sponsors & Collaborators

• Uppsala University: lead

Study Sites (1)

Akademiska sjukhuset

Uppsala, 75123, Sweden

RECRUITING

Study Officials

• Oskar Nensén, MD, PhD

  Uppsala University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Oskar Nensén, MD, PhD

CONTACT

+46186110000; oskar.nensen@uu.se

Niclas Högberg, MD, PhD

CONTACT

+46186110000; niclas.hogberg@uu.se

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 2, 2025
• First Posted: January 20, 2026
• Study Start: December 1, 2025
• Primary Completion (Estimated): January 1, 2030
• Study Completion (Estimated): January 1, 2030
• Last Updated: January 20, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will share

Locations

SE (1)