Erector Spinae Plane Block Versus Serratus Anterior Plane Block in VATS

NCT06996691 | Recruiting

• 1 other identifier: FMASU MS 145/2025
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Pain control remains challenging in patients undergoing video-assisted thoracoscopic surgery (VATS). It is advised to use a regional block to lower postoperative opioid usage. This study evaluates efficacy of Erector spinae plane (ESP) block in comparison to Serratus anterior plane block (SAP) in pain management for patients undergoing video-assisted thoracoscopic surgery(VATS).

Conditions

Video Assisted Thoracic Surgery (VATS)

Keywords

VATS; Erector spinae plane block; Serratus anterior plane block

Outcome Measures

Primary Outcomes (1)

• post operative opioid consumption

  post operative meperidine consumption throughout

  24 hours post operative

Secondary Outcomes (2)

• intraoperative fentanyl consumption

  during the surgery

• the numerical rating scale

  24 hours post operative

Study Arms (2)

Group A: Erector spinae block group

ACTIVE COMPARATOR

After selecting the target transverse process for the nerve block, place the transducer in a paramedian sagittal orientation, approximately 2cm away from the midline (spinous processes), and try to vizualize the transverse process at the level of T5 Complete the nerve block with 30ml of 0.25% levobupivacaine for erector spinae block

Procedure: Erector Spinae Plane Block (ESPB) group

group B: Serratus anterior block group

ACTIVE COMPARATOR

High-frequency linear transducer should be placed on the patient's midaxillary line in the transverse plane, at the level of the fifth rib. With the rib, pleural line, and overlying serratus anterior and latissimus dorsi muscles visualized. Then, using ultrasound guidance, the needle is advanced in-plane and the local anesthetic is injected anteriorly to the rib and deep to the serratus anterior. After opening the fascial plane, a volume of dilute local anesthetic, 30 mL of 0.25% levobupivacaine, should be gradually injected.

Procedure: Serratus Anterior Plane Block (SAPB) group

Interventions

Erector Spinae Plane Block (ESPB) group PROCEDURE

30ml of 0.25% levobupivacaine for erector spinae block at level of T5

Group A: Erector spinae block group

Serratus Anterior Plane Block (SAPB) group PROCEDURE

30 mL of 0.25% levobupivacaine injected anteriorly to the rib and deep to the serratus anterior at level of 5 th rib

group B: Serratus anterior block group

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• body mass index (BMI)=18 to 40 kg/m2

You may not qualify if:

• Contraindications to regional anesthesia as bleeding disorders , allergy to local anesthetic or infection at block site
• pre-existing chronic pain
• history of opiate abuse
• sepsis

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

faculty of medicine Ain Shams University

Cairo, 02, Egypt

RECRUITING

MeSH Terms

Interventions

Population Groups; Saposins

Intervention Hierarchy (Ancestors)

Demography; Population Characteristics; Sphingolipid Activator Proteins; Coenzymes; Enzymes and Coenzymes

Central Study Contacts

abdallah M soudi, M.D.56k

CONTACT

+201111228925; Dr.soudi2014@med.asu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2025
• First Posted: May 30, 2025
• Study Start: May 1, 2025
• Primary Completion: July 31, 2025
• Study Completion: August 15, 2025
• Last Updated: May 30, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF

Locations

EG (1)