Effect of Green Light Exposure at Different Times on the Pain of Subjects

NCT07033949 | Not Yet Recruiting

• 1 other identifier: GLE
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Patients who met the criteria and needed to undergo elective surgery via arterial and venous puncture were included in this center. They were randomly divided into three time periods (8:00-9:00, 12:00-13:00, 16:00-17:00) and were exposed to green light (experimental group) and transparent light (control group) respectively. The effects of green light exposure on acute perioperative pain in patients were observed at different times.

Conditions

Pain

Keywords

Acute Pain; Green light

Outcome Measures

Primary Outcomes (1)

• Pain intensity during arteriovenous puncture

  assessed using number rating scale (0 to 10, which higher scores mean a worse pain intensity)

  The pain score during arterial puncture which about 2-3min

Secondary Outcomes (4)

• Pain sensitivity

  from the time before to 30 min after light exposure

• Analgesic consumption during surgery

  From surgery beginning to the ending of the surgery

• Pain intensity after surgery

  From ending of the surgery to 24 hours after surgery

• Analgesic consumption after surgery

  From ending of the surgery to 24 hours after surgery

Other Outcomes (1)

• Heart rate

  from before arterial puncture to 5min after the arterial puncture

Study Arms (2)

Green light exposure group

EXPERIMENTAL

Before performing the arterial puncture, expose to green light for 30 minutes.

Device: Green light glasses

Transparent light exposure

PLACEBO COMPARATOR

Before performing the arterial puncture, expose to Transparent light for 30 minutes.

Device: Transparent light exposure

Interventions

Green light glasses DEVICE

Exposure to green light for 30 minutes

Green light exposure group

Transparent light exposure DEVICE

Exposure to transparent light for 30 minutes

Transparent light exposure

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age range: 18 - 50 years old.
• ASA classification: I - III.
• Planned to undergo abdominal surgeries requiring general anesthesia and arterial puncture (this is not necessary for the healthy volunteer group).
• Obtained informed consent from the patients.

You may not qualify if:

• Skin ulceration, allergic reactions, or dermatitis at the tested area.
• Long-term use of analgesics or psychiatric medications.
• History of color blindness or uncorrected cataracts.
• Severe cardiovascular or respiratory diseases, inflammatory disorders, etc.
• Failure of the first arterial puncture.
• Communication difficulties, etc.

Sponsors & Collaborators

• The Second Affiliated Hospital of Chongqing Medical University: lead

Study Sites (1)

The Second Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 4000000, China

Location

MeSH Terms

Conditions

Pain; Acute Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

guangyou ph.D Duan

CONTACT

18323376014; duangy@hospital.cqmu.edu.cn

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 15, 2025
• First Posted: June 24, 2025
• Study Start: July 1, 2025
• Primary Completion: October 19, 2025
• Study Completion: October 19, 2025
• Last Updated: June 27, 2025

Record last verified: 2025-06

Locations

CN (1)