A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy

NCT06553495 | Active Not Recruiting

• 1 other identifier: 2024-098
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for postoperative pain management of liver surgery.

Conditions

Pain

Outcome Measures

Primary Outcomes (1)

• The number of effective compressions of the analgesic pump within 24 hours after surgery

  Within 24 hours after the operation

Study Arms (2)

intertransverse nerve block

EXPERIMENTAL

To study the analgesic effect of intertransverse nerve block after endoscopic hepatectomy

Other: Nerve block

paravertebral nerve block

PLACEBO COMPARATOR

To study the analgesic effect of paravertebral nerve block after endoscopic hepatectomy

Other: Nerve block

Interventions

Nerve block OTHER

Analgesic effect of different nerve blocks

intertransverse nerve block; paravertebral nerve block

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years old adult, BMI\<27.9kg/m2
• : 2. American Society of Anesthesiologists ASA Grade I-III
• : 3. Patients with laparoscopic partial liver resection such as liver tumors
• : 4. Willing to participate in this study and sign the informed consent form

You may not qualify if:

• \. The patient or family member refuses to sign the informed consent form
• \. Blood coagulation dysfunction, local infection
• \. Those who have communication, communication disorders or mental abnormalities
• \. Patients with severe heart, pulmonary and renal insufficiency or patients with central system diseases
• \. For any reason, it cannot be matched with the study or the researcher believes that it is not appropriate to be included in this experiment.

Sponsors & Collaborators

• Jie Chen: lead

Study Sites (1)

The Second Affiliated Hospital Of Chongqing Medical University

Chongqing, Chongqing Municipality, 400000, China

Location

MeSH Terms

Conditions

Pain

Interventions

Nerve Block

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Anesthesia, Conduction; Anesthesia; Anesthesia and Analgesia; Denervation; Neurosurgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: 临床教授

Study Record Dates

• First Submitted: August 12, 2024
• First Posted: August 14, 2024
• Study Start: August 1, 2024
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: August 14, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)