The Effects of Non Harmonic and White Noise on Human Pain Sensitivity: a Study of Healthy Volunteers

NCT06165757 | Completed

• 1 other identifier: Noise and pain sensitivit
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Study the effects of 60dB and 80dB white noise, 50-70dB and 70-90dB non harmonic tones on the basic pain threshold of subjects, including the threshold and tolerance of electrical stimulation pain,the threshold and tolerance of cold pain stimulation, and the threshold and tolerance of tenderness stimulation.

Conditions

Pain

Keywords

Noise; Pain

Outcome Measures

Primary Outcomes (3)

• mechanical pain sensitivity

  Each participant was measured using the pressure pain threshold and tolerance (tested by a pressure meter), which lower value present higher pain sensitivity

  from the study beginning to 30 min after the procedure

• cold pain sensitivity

  Each participant was measured using the cold pain threshold and tolerance (tested by immersion the hand in 4℃ water), which lower value present higher pain sensitivity

  from the study beginning to 30 min after the procedure

• electrical pain sensitivity

  Each participant was measured using the cold pain threshold and tolerance (tested by a electrical stimulator), which lower value present higher pain sensitivity

  from the study beginning to 30 min after the procedure

Study Arms (1)

noise on pain

EXPERIMENTAL

Comparison of pain sensitivity before and after hearing noise among 15 subjects in each group.

Behavioral: noise stimulation

Interventions

noise stimulation BEHAVIORAL

Apply non harmonic and white noise sound stimuli to the subjects, and then measure the threshold and tolerance values of pressure pain, cold pain, and electrical pain.

noise on pain

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Between the ages of 18 and 35, regardless of gender
• No serious chronic diseases
• There is no self-reported history of chronic opioid drug use or neuropathy

You may not qualify if:

• A history of alcohol or drug abuse
• Pregnant or lactating
• Severe cardiovascular, kidney, or liver diseases

Sponsors & Collaborators

• The Second Affiliated Hospital of Chongqing Medical University: lead

Study Sites (1)

Department of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University

Chongqing, Chongqing Municipality, 400010, China

Location

MeSH Terms

Conditions

Pain

Interventions

Transcranial Direct Current Stimulation

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electric Stimulation Therapy; Therapeutics; Convulsive Therapy; Psychiatric Somatic Therapies; Behavioral Disciplines and Activities; Electroshock; Psychological Techniques

Study Officials

• He Huang, MD

  The Second Affiliated Hospital, Chongqing Medical University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 9, 2023
• First Posted: December 11, 2023
• Study Start: October 10, 2023
• Primary Completion: January 20, 2024
• Study Completion: January 20, 2024
• Last Updated: March 13, 2024

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will share

Locations

CN (1)