NCT07020234

Brief Summary

Few people realize that environmental pollution and some behaviors like physical activity and tobacco smoking can affect their health by "turning on" or "turning off" certain genes through a process called "epigenetic modification." This study will develop and test strategies for communicating about epigenetics that are understandable and that increase acceptance of using epigenetics in clinical settings.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,040

participants targeted

Target at P75+ for not_applicable healthy

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 5, 2025

Completed
7 days until next milestone

Study Start

First participant enrolled

June 12, 2025

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 13, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 18, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 18, 2025

Completed
Last Updated

September 29, 2025

Status Verified

September 1, 2025

Enrollment Period

1 month

First QC Date

June 5, 2025

Last Update Submit

September 26, 2025

Conditions

Healthy

Keywords

EpigenomicsEpigeneticsGenetics, BehavioralBioethics

Outcome Measures

Primary Outcomes (1)

  • Knowledge & understanding of epigenetics Information

    We will measure this outcome using a sum score of correct answers for 8 individual items.

    At enrollment

Secondary Outcomes (2)

  • Acceptability of epigenetics information

    At enrollment

  • Perceptions of epigenetic information

    At enrollment

Study Arms (2)

Epigenetics Video

EXPERIMENTAL

Participants will watch a brief (\<5 minute) video about the concept of Epigenetics

Behavioral: Epigenetics Video

Nanotechnology Video

ACTIVE COMPARATOR

Participants will watch a brief (\<5 minute) video about nanotechnology

Behavioral: Nanotechnology Video

Interventions

Epigenetics VideoBEHAVIORAL

Educational video about health and epigenetics.

Epigenetics Video
Nanotechnology VideoBEHAVIORAL

Educational video about nanotechnology

Nanotechnology Video

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • English language speaker,
  • Identify as one of five racial/ethnic groups:
  • Non-Hispanic White
  • Non-Hispanic Black,
  • Non-Hispanic Asian
  • Non-Hispanic Indigenous (i.e., Alaska Native/Native Hawaiians/American Indian/Other Pacific Islander)
  • Hispanic (all races)

You may not qualify if:

  • Self-identify as a genetics expert

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Washington University School of Medicine

St Louis, Missouri, 63110, United States

Location

MeSH Terms

Conditions

Behavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 5, 2025

First Posted

June 13, 2025

Study Start

June 12, 2025

Primary Completion

July 18, 2025

Study Completion

July 18, 2025

Last Updated

September 29, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will share

Locations

US(1)