Sleep and Maximal Fat Oxidation

NCT07015008 | Completed

• 1 other identifier: CEID/2023/6/119_2
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Introduction: Despite the awareness of the importance of sleep in our lives, especially for athletes, the consequences of poor rest on sports performance are not well understood. Furthermore, the interaction between complete and partial sleep deprivation over one night and sleeping the usual hours for each person remains unclear. Objectives: The aim of this study is to evaluate the effects of sleep deprivation on maximal fat oxidation (MFO) in male and female participants.

Conditions

Sleep Deprivation

Outcome Measures

Primary Outcomes (1)

• Maximal Fat Oxidation Rate

  g/min using a metabolic chart

  Through study completion, an average of 4 weeks

Secondary Outcomes (2)

• Fat mass

  Through study completion, an average of 4 weeks

• Fat-free mass

  Through study completion, an average of 4 weeks

Study Arms (4)

8h Sleep (at home)

PLACEBO COMPARATOR

Arm Description: Participants sleep 8h at home

Behavioral: Sleep deprivation; Behavioral: Sleep place

8h Sleep (Laboratory)

EXPERIMENTAL

Participants sleep 8h in the lab

Behavioral: Sleep deprivation; Behavioral: Sleep place

4h Sleep (Laboratory)

EXPERIMENTAL

Participants sleep 4h in the laboratory

Behavioral: Sleep deprivation

0h Sleep (Laboratory)

EXPERIMENTAL

Participants sleep 0h in the laboratory

Behavioral: Sleep deprivation

Interventions

Sleep deprivation BEHAVIORAL

Partial (4h) or total (0h) sleep deprivation

0h Sleep (Laboratory); 4h Sleep (Laboratory); 8h Sleep (Laboratory); 8h Sleep (at home)

Sleep place BEHAVIORAL

8h sleep at home or in the laboratory

8h Sleep (Laboratory); 8h Sleep (at home)

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age between 18 and 35 years.
• Body Mass Index (BMI) \< 25 kg/m².
• Resistance-trained individuals (more than 2 years of structured training).
• Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from exercising.
• Participants must be able to perform the tests described in the following section.

You may not qualify if:

• History of neuromuscular diseases, heart disease, or conditions that may affect liver or muscle metabolism.
• Use of drugs, stimulants, or sports supplements that could interfere with the dietary supplement used in the study.
• Sedentary habits (less than 150 minutes/week of moderate exercise).
• Having undergone prolonged periods of physical inactivity in the 6 months prior to the study.
• Engaging in strenuous exercise within 48 hours prior to the tests.
• Failure to replicate the same food intake on both experimental days.
• Consumption of caffeine or any other stimulant the day before the tests.

Sponsors & Collaborators

• University of Alcala: lead

Study Sites (1)

Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá

Alcalá de Henares, Madrid, Spain

Location

MeSH Terms

Conditions

Sleep Deprivation

Condition Hierarchy (Ancestors)

Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Statistician
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 23, 2025
• First Posted: June 11, 2025
• Study Start: January 1, 2025
• Primary Completion: April 30, 2025
• Study Completion: April 30, 2025
• Last Updated: June 11, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will share

Locations

ES (1)