NCT07008807

Brief Summary

Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. The continuous pull and action of facial muscles can influence the development and positioning of underlying soft tissues and even, over extended periods, potentially impact skeletal structures.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 20, 2025

Completed
12 days until next milestone

Study Start

First participant enrolled

June 1, 2025

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 6, 2025

Completed
25 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2025

Completed
Last Updated

June 6, 2025

Status Verified

May 1, 2025

Enrollment Period

1 month

First QC Date

May 20, 2025

Last Update Submit

May 29, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Facial Electromyography (EMG)

    Day 1

  • Facial Asymmetry Measurement

    assesses differences between the two sides of the face using various techniques, both two-dimensional (2D) and three-dimensional (3D)

    Day 1

Secondary Outcomes (1)

  • Demographic and Clinical Data

    Day 1

Study Arms (2)

group A

people with facial asymmetry

Group B

control group of healthy normal people

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Presenting with noticeable facial asymmetry.

You may qualify if:

  • Presenting with noticeable facial asymmetry
  • Age \> 16 years
  • General good health
  • Absence of specific neurological conditions affecting facial muscles.
  • Absence of congenital facial disorders that might cause facial asymmetry, like hemifacial microsomia and cleft lip and palate syndromes.

You may not qualify if:

  • History of facial trauma or surgery
  • Diagnosed Neuromuscular Disorders
  • Active facial infections.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

orthodontic outpatient clinic, and students at Faculty of Dentistry, Alsalam University, Egypt

Tanta, Tanta, Egypt

Location

Related Publications (2)

  • 4. Kowner, R. (1996). Facial asymmetry and attractiveness judgment in Western and Japanese cultures. Journal of Social Behavior and Personality, 11(2), 301-314.

    BACKGROUND
  • Ferrario VF, Dellavia C, Tartaglia GM, Turci M, Sforza C. Soft tissue facial morphology in obese adolescents: a three-dimensional noninvasive assessment. Angle Orthod. 2004 Feb;74(1):37-42. doi: 10.1043/0003-3219(2004)0742.0.CO;2.

    PMID: 15038489BACKGROUND

MeSH Terms

Conditions

Facial Asymmetry

Condition Hierarchy (Ancestors)

Pathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Central Study Contacts

Mohammed E. Ali, PhD

CONTACT

Nehad A. Abo-zaid, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of Physical Therapy for surgery

Study Record Dates

First Submitted

May 20, 2025

First Posted

June 6, 2025

Study Start

June 1, 2025

Primary Completion

July 1, 2025

Study Completion

August 1, 2025

Last Updated

June 6, 2025

Record last verified: 2025-05

Locations