NCT07002775

Brief Summary

Use Transesophageal ultrasound in OHCA patients to identify the proper CPR position

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
8mo left

Started Jan 2025

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress64%
Jan 2025Jan 2027

Study Start

First participant enrolled

January 23, 2025

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

May 6, 2025

Completed
29 days until next milestone

First Posted

Study publicly available on registry

June 4, 2025

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 23, 2026

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

January 23, 2027

Expected
Last Updated

June 4, 2025

Status Verified

January 1, 2025

Enrollment Period

1 year

First QC Date

May 6, 2025

Last Update Submit

May 25, 2025

Conditions

Cardiac Arrest (CA)

Keywords

OHCATEE

Outcome Measures

Primary Outcomes (2)

  • cardiac output

    built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography)

    check cardiac output while CPR(Periprocedural)(after TEE insertion) in head up and supine position

  • stroke volume

    built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare,

    check stroke volume while CPR(Periprocedural)(after TEE insertion) in head up and supine position

Study Arms (1)

CPR position

OTHER

Same patient with different CPR position : head up or supine

Device: Transesophageal ultrasound

Interventions

Transesophageal ultrasoundDEVICE

Transesophageal ultrasound with built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography) to evaluate stroke volume and cardiac output in different position with the same person

CPR position

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Out of hospital cardiac arrest patients

You may not qualify if:

  • DNR was signed,
  • Age under 18
  • Trauma patients
  • Patients hard to establish advanced airway
  • C spine injury patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Chang Bing Show Chawan Memorial Hospital

Changhua, Taiwan

Location

National Taiwan University Hospital

Taipei, Taiwan

Location

Related Publications (4)

  • Moore JC, Salverda B, Lick M, Rojas-Salvador C, Segal N, Debaty G, Lurie KG. Controlled progressive elevation rather than an optimal angle maximizes cerebral perfusion pressure during head up CPR in a swine model of cardiac arrest. Resuscitation. 2020 May;150:23-28. doi: 10.1016/j.resuscitation.2020.02.023. Epub 2020 Feb 27.

    PMID: 32114071BACKGROUND

  • Moore JC, Holley J, Segal N, Lick MC, Labarere J, Frascone RJ, Dodd KW, Robinson AE, Lick C, Klein L, Ashton A, McArthur A, Tsangaris A, Makaretz A, Makaretz M, Debaty G, Pepe PE, Lurie KG. Consistent head up cardiopulmonary resuscitation haemodynamics are observed across porcine and human cadaver translational models. Resuscitation. 2018 Nov;132:133-139. doi: 10.1016/j.resuscitation.2018.04.009. Epub 2018 Apr 24.

    PMID: 29702188BACKGROUND

  • Kim T, Shin SD, Song KJ, Park YJ, Ryu HH, Debaty G, Lurie K, Hong KJ. The effect of resuscitation position on cerebral and coronary perfusion pressure during mechanical cardiopulmonary resuscitation in porcine cardiac arrest model. Resuscitation. 2017 Apr;113:101-107. doi: 10.1016/j.resuscitation.2017.02.008. Epub 2017 Feb 16.

    PMID: 28215591BACKGROUND

  • Debaty G, Shin SD, Metzger A, Kim T, Ryu HH, Rees J, McKnite S, Matsuura T, Lick M, Yannopoulos D, Lurie K. Tilting for perfusion: head-up position during cardiopulmonary resuscitation improves brain flow in a porcine model of cardiac arrest. Resuscitation. 2015 Feb;87:38-43. doi: 10.1016/j.resuscitation.2014.11.019. Epub 2014 Nov 28.

    PMID: 25447353BACKGROUND

MeSH Terms

Conditions

Heart Arrest

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • WANCHING LIEN

    National Taiwan University Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 6, 2025

First Posted

June 4, 2025

Study Start

January 23, 2025

Primary Completion

January 23, 2026

Study Completion (Estimated)

January 23, 2027

Last Updated

June 4, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will share

all collected IPD

Shared Documents
STUDY PROTOCOL
Time Frame
starting 6 months after publication

Locations

TW(2)