Educational Kinesiology Program's Effect on Cognition, Manual Dexterity and Bimanual Coordination in MS Patients

NCT07002151 | Completed DMC

• 1 other identifier: effect of EKP on cognition
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

the purpose of this study was to evaluate the usefulness of educational kinesiology program to improve cognitive impairement, manual dexterity and bimanual coordination in patients with relapsing remitting multiple sclerosis. the study evaluated some domain of cognition as (attention \& concentration, figural memory, reaction behavior and logical reasoning) manual dexterity and bimanual coordination were also evaluated of individuals with multiple sclerosis who went through the traditional as compared to others who used educational kinesiology training as part of their therapy.

Conditions

Relapsing-remitting Multiple Sclerosis

Keywords

RRMS; cognitive impairment; manual dexterity; bimanual coordination; educational kinesiology program

Outcome Measures

Primary Outcomes (1)

• cognition

  the rate of improvement in cognition assessed by Rehacom system V 6.10.2.0 software.

  baseline assessment and after 12 sessions of educational kinesiology program training and conventional upper extremity coordination exercise training 3 sessions per week for 4 weaks

Secondary Outcomes (1)

• manual dexterity and bimanual coordination

  baseline assessment and after 12 sessions of educational kinesiology training and conventional upper extremities coordination exercises training 3 sessions per week for 4 weaks

Study Arms (2)

study group

EXPERIMENTAL

experimental arm was recieved educational kinesiology program and conventional upper extremity coordination exercises as intervention.Respondents were explained about the Educational kinesiology program.by the therapist. The exercise program was given three times weekly for four weeks. Duration of the session was15 min ), the patients did 5 exercises, each exercise was done for 3 minutes,when patient felt fatigue during performing the exercise he or she stopped then continued after relaxation till reaching 3 min for each one . All exercises were done from sitting position.

Other: educational kinesiology training program intervention for study group; Other: conventional upper extremities coordination training for both arms experimental and comparator (study and control) groups

control group

ACTIVE COMPARATOR

received conventional physical therapy program in form of upper extremities coordination training

Other: conventional upper extremities coordination training for both arms experimental and comparator (study and control) groups

Interventions

educational kinesiology training program intervention for study group OTHER

The Educational kinesiology program were included : (Cross crawl) Sit or stand and with the right-hand elbow touch the left knee and vice versa. (The owl) Bring one hand up to the opposite shoulder and hold a pinch around the trapezius muscle between the neck and shoulder. the thumb should be on one side of the muscle and the other fingers clasping around the other side. Turn the head to the same side as thehand is gripping and take a deep breath. Slowly exhale as bringing the head gently around to the other side. Repeat this movement one more time. (The arm activation) Hold one arm next to the ear. Exhale gently while activating the muscles by pushing the arm against the other hand in four directions (front, back, in and away). (The Energizer) Place the head on the desk in front exhale and inhale while coming up and try to hyperextend the neck carefully. (cook's hook-up) put the left ankle over your right knee. Next, hook the right hand around the left ankle.

Also known as: brain gym exercises

study group

conventional upper extremities coordination training for both arms experimental and comparator (study and control) groups OTHER

Bimanual coordination,Hand-arm coordination ,Drinking \& Strength training

control group; study group

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Male or female aged from 18-50 years.
• Patients with relapsing remitting MS (RRMS).
• EDSS scores for (RRMS) is ranging from 2.5 to 5.5 with a pyramid function score less than 2.
• Gave their oral and written consent to participate in the training.
• Adequate vision and hearing for completion of the study protocol, as indicated by the ability to follow written and oral instructions during screening.
• Stable medical condition.

You may not qualify if:

• Patients with communication problems.
• Patients with a history of previous neurologic diseases or disorders.
• Patients with other types of MS.
• In co-operative patients.
• Unhealed fracture, contracture, pressure sores that might interfere with training.
• Untreated psychiatric disorders or ongoing drug abuse.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physicaltherapy

Cairo, Egypt

Location

Related Publications (2)

• Alharthi HM, Almurdi MM. Association between cognitive impairment and motor dysfunction among patients with multiple sclerosis: a cross-sectional study. Eur J Med Res. 2023 Mar 2;28(1):110. doi: 10.1186/s40001-023-01079-6.

  PMID: 36864515 BACKGROUND

• Lyle KB, Dombroski BA, Faul L, Hopkins RF, Naaz F, Switala AE, Depue BE. Bimanual coordination positively predicts episodic memory: A combined behavioral and MRI investigation. Brain Cogn. 2017 Nov;118:71-79. doi: 10.1016/j.bandc.2017.07.009. Epub 2017 Aug 9.

  PMID: 28800429 BACKGROUND

MeSH Terms

Conditions

Multiple Sclerosis, Relapsing-Remitting; Cognitive Dysfunction

Interventions

Population Groups

Condition Hierarchy (Ancestors)

Multiple Sclerosis; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Demography; Population Characteristics

Study Officials

• eman s fayez, doctorate

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: randomized control trial

Study Record Dates

• First Submitted: May 18, 2025
• First Posted: June 3, 2025
• Study Start: January 10, 2024
• Primary Completion: May 10, 2025
• Study Completion: May 10, 2025
• Last Updated: June 3, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)