Key Insights

Highlights

Success Rate

83% trial completion

Published Results

37 trials with published results (29%)

Research Maturity

89 completed trials (71% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

14.3%

18 terminated out of 126 trials

Success Rate

83.2%

-3.3% vs benchmark

Late-Stage Pipeline

37%

46 trials in Phase 3/4

Results Transparency

42%

37 of 89 completed with results

Key Signals

37 with results83% success18 terminated

Data Visualizations

Phase Distribution

96Total
Not Applicable (11)
Early P 1 (1)
P 1 (11)
P 2 (27)
P 3 (22)
P 4 (24)

Trial Status

Completed89
Terminated18
Unknown5
Withdrawn5
Active Not Recruiting4
Recruiting3

Trial Success Rate

83.2%

Benchmark: 86.5%

Based on 89 completed trials

Clinical Trials (126)

Showing 20 of 20 trials
NCT07503340Phase 2Not Yet RecruitingPrimary

A Study to Evaluate Pharmacokinetics, Safety, Tolerability, Immunogenicity and Pharmacodynamic Effects of Subcutaneous Ocrelizumab Administration in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)

NCT07517185Phase 2Not Yet RecruitingPrimary

The HIt HArd and hiT Early in Multiple Sclerosis Trial

NCT05090371Phase 4Active Not RecruitingPrimary

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

NCT04530318Phase 2Active Not RecruitingPrimary

Dendritic Cells Therapy Combined With Immunomodulatory Treatment in Multiple Sclerosis

NCT01805336Not ApplicableCompletedPrimary

Assessment of Attentional and Executive Disorders in Multiple Sclerosis Using Techniques of Virtual Reality

NCT05758831Phase 3Recruiting

RItuximab Versus Ocrelizumab in Relapsing-remitting Multiple Sclerosis.

NCT05123703Phase 3Active Not RecruitingPrimary

A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis (RRMS)

NCT04940065CompletedPrimary

Special Drug-use Surveillance for Kesimpta for s.c. Injection 20 mg Pen

NCT06586177RecruitingPrimary

Understanding the 'Durable Effect' Concept of B-cell Modulating Therapies

NCT05755061Phase 1Active Not Recruiting

WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis

NCT02283853Phase 3CompletedPrimary

Phase 3 Efficacy and Safety Study of BG00012 in Pediatric Subjects With Relapsing-remitting Multiple Sclerosis (RRMS)

NCT07002151Not ApplicableCompletedPrimary

Educational Kinesiology Program's Effect on Cognition, Manual Dexterity and Bimanual Coordination in MS Patients

NCT02975349Phase 2TerminatedPrimary

A Study of Efficacy and Safety of M2951 in Participants With Relapsing Multiple Sclerosis

NCT03193866CompletedPrimary

COMparison Between All immunoTherapies for Multiple Sclerosis.

NCT03825601Not ApplicableCompleted

PET with [18F]Flumazenil As an Index of Neurodegeneration in MS

NCT04997148CompletedPrimary

Effectiveness of Cladribine Tablets in Participants With Highly-active Relapsing Multiple Sclerosis (CAMELOT-MS)

NCT05423769CompletedPrimary

Safety and Effectiveness of Generic Fingolimod (Sphingomod®, Hikma) in Patients With Relapsing-Remitting Multiple Sclerosis in Egypt

NCT06526000Completed

Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies

NCT01706107TerminatedPrimary

Canadian Multicenter Observational Study of Tysabri in Early Relapsing Remitting Multiple Sclerosis Participants

NCT00771043Phase 4WithdrawnPrimary

A Proof-of-Concept Study to Correlate Retinal Nerve Fiber Layer Changes in Patients With Multiple Sclerosis Treated With Natalizumab or Interferon Beta 1-a

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