Effectiveness Evaluation of the "Mosquito-Free Campus" Initiative on Dengue Fever Prevention and Control: A Cluster Randomized Controlled Trial

NCT07002021 | Not Yet Recruiting DMC

• 1 other identifier: SunYat-senU20250516
• Study Type: interventional
• Target: 3,940
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this cluster randomized controlled trial is to evaluate the effect of health education interventions on the score of the knowledge, attitudes, and practices (KAP) of dengue in in primary and middle school students in the city of Guangzhou and Foshan in China. Individuals aged 6 to 15 years who are in grades 1-9 in primary schools in Guangzhou and Foshan will be enrolled. 20 primary schools will be randomly selected, with half designated as intervention group schools and the remaining half as control group schools. The intervention group will receive a health education intervention focused on dengue prevention every semester for 6 months, while the control group will continue with their routine school health education for 6 months. Researchers will compare the differences in the score of the KAP of dengue between the intervention and control groups after 6 months to see if health education can improve knowledge, attitudes and practices of dengue among primary and middle school students.

Conditions

Dengue; Infection Prevention

Keywords

health education; schools; China

Outcome Measures

Primary Outcomes (1)

• scores of the knowledge, attitudes, and practices (KAP) of dengue

  Regarding the knowledge, attitudes, and practices of dengue, each correct answer for the health literacy research questionnaire will be scored as one point, with incorrect answers receiving no points.

  From enrollment to the end of intervention in 6 months

Secondary Outcomes (1)

• mosquito vector index

  From enrollment to the end of intervention in 6 months

Study Arms (2)

Intervention

EXPERIMENTAL

The intervention group will receive a health education intervention focused on dengue prevention every semester for 6 months

Combination Product: Health education

No Intervention: Control

NO INTERVENTION

The control group will continue with their routine school health education for 6 months.

Interventions

Health education COMBINATION_PRODUCT

The intervention group will receive a health education intervention focused on dengue prevention and campus environmental governance, while the control group will continue with their standard school health education without any additional intervention. An health education including the knowledge of dengue fever, harm of mosquitoes, and measures of mosquito control, will be developed and reviewed by an expert group. The campus environmental governance includes organizing campus environmental cleaning once a week, focusing on removing mosquito breeding places such as water containers.

Intervention

Eligibility Criteria

• Age: 6 Years - 15 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Primary and middle school students within the age range of 6-15 years.
• The primary and middle schools are located in Yuexiu District, Baiyun District of Guangzhou city or Nanhai District of Foshan City.
• The schools have the necessary infrastructure, management level and resource allocation to participate in dengue fever prevention and control.
• The schools agree to implement the intervention measures during the research period.
• The schools are willing to provide baseline data and participate in subsequent assessments before the intervention is implemented.

You may not qualify if:

• Unwilling to participate in the project.
• Participants (students or staff members) are unable to participate in the intervention or withdraw from the study due to personal reasons.

Sponsors & Collaborators

• Sun Yat-sen University: lead

MeSH Terms

Conditions

Dengue; Health Education

Condition Hierarchy (Ancestors)

Mosquito-Borne Diseases; Vector Borne Diseases; Infections; Arbovirus Infections; Virus Diseases; Flavivirus Infections; Flaviviridae Infections; RNA Virus Infections; Hemorrhagic Fevers, Viral; Adherence Interventions; Medication Adherence; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Central Study Contacts

Lin Xu, PhD

CONTACT

(86) 20-8733-5523; xulin27@mail.sysu.edu.cn

Weixiang Gao, Master

CONTACT

(86) 17328625687; gaowx7@mail2.sysu.edu.cn

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: May 25, 2025
• First Posted: June 3, 2025
• Study Start: June 15, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: June 3, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share