Impact of Health Education on Knowledge, Attitude and Practice of Post-exposure Prophylaxis

NCT07330427 | Recruiting DMC

• 1 other identifier: Post-exposure prophylaxis
• Study Type: interventional
• Target: 340
• Locations: 1 country
• Sites: 1

Brief Summary

Occupational exposure to blood-borne pathogens, such as human immune-deficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) for healthcare workers through contact with human blood and body fluids has become a major health concern as it poses a risk of transmission of these infectious agents. According to the World Health Organization (WHO) report, about three million HCWs are exposed to blood-borne pathogens each year, of which 170,000 are exposed to HIV infections, 2 million to HBV infections, and 0.9 million to HCV infections. Most of the time, healthcare providers get exposure through the splash of blood or other body fluids into the eyes, nose, or mouth or nonintact skin exposure, and percutaneous injury occurs as a result of a break in the skin caused by a needlestick or sharps contaminated with blood or body fluids

Conditions

Post Exposure Prophylaxis

Outcome Measures

Primary Outcomes (1)

• Health Practice Change

  Assessment of participants after taking health education lecturers about post-exposure prophylaxis regrading to knowledge, attitude and practice and this done by questionnaire as :The questionnaire consisted of three sections assessing knowledge, attitude, and practice regarding post-exposure prophylaxis (PEP). Section B assessed knowledge using nine close-ended questions, with adequate knowledge defined as ≥75% correct answers. Section C included seven items evaluating attitudes toward the importance and effectiveness of PEP, with scores ≥75% indicating a good attitude. Section D assessed PEP practices through nine questions, and good practice was defined as positive responses to more than 75% of items.

  3 Months

Study Arms (1)

Health Care workers

EXPERIMENTAL

About 340 participants of heath care workers undergoing assessment of knowledge, attitude and practice about post-exposure prophylaxis among health care workers at Aswan university hospital, Egypt Then they will undergo lecturers about about post-exposure prophylaxis, then reassessment will be done after 3 months

Procedure: Health Education

Interventions

Health Education PROCEDURE

1. Assess the baseline knowledge, attitudes and practices of health care workers at Aswan university hospital towards postexposure prophylaxis against blood-borne viral infection. 2. Provide an intense post exposure prophylaxis health education sessions. 3. Evaluate changes in post exposure prophylaxis knowledge, attitudes and practices after the health education intervention.

Health Care workers

Eligibility Criteria

• Age: 19 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• HCWs at the selected departments (physicians, nurses and housekeepers).
• Age \>18 years old and below 60 years old in both Genders.
• HCWs which have direct contact with blood and body fluids.

You may not qualify if:

• Age\<18 years old and above 60 years old.
• Non-medical staff at Aswan university hospital.
• Health care workers which have no contact with blood or body fluids.

Sponsors & Collaborators

• Aswan University: lead

Study Sites (1)

Aswan faculty of Medicine

Aswān, Egypt

RECRUITING

Study Officials

• Shaimaa Sayed Abdelrheem, M.D

  Associate Professor of Public Health and Community Medicine, Faculty of medicine, Aswan University

  STUDY CHAIR

Central Study Contacts

Fatma Ali Mahmoud Hussein, MSc

CONTACT

+201153368599; fatma.mahmoud@med.aswu.edu.eg

Shaimaa Sayed Abdelrheem, Professor

CONTACT

+201064031040; dr_shimaasayed@yahoo.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Demonstrator at Public Health and Community Medicine, Faculty of medicine

Study Record Dates

• First Submitted: December 11, 2025
• First Posted: January 9, 2026
• Study Start: June 1, 2025
• Primary Completion: February 1, 2026
• Study Completion: February 1, 2026
• Last Updated: January 9, 2026

Record last verified: 2025-06

Locations

EG (1)