NCT07000864

Brief Summary

The purpose of this study is to obtain unused resected tumor tissue sample and associated clinical data from patients enrolled in this study to research ex vivo treatment response and integrity of tumor microenvironment using omics analysis and imaging while maintaining cell stability in a live environment.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
24mo left

Started Jul 2025

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress33%
Jul 2025Jun 2028

First Submitted

Initial submission to the registry

May 23, 2025

Completed
11 days until next milestone

First Posted

Study publicly available on registry

June 3, 2025

Completed
28 days until next milestone

Study Start

First participant enrolled

July 1, 2025

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2028

Last Updated

May 22, 2026

Status Verified

May 1, 2026

Enrollment Period

2.9 years

First QC Date

May 23, 2025

Last Update Submit

May 19, 2026

Conditions

CancerTumor

Outcome Measures

Primary Outcomes (1)

  • Tissue response to treatment

    Tumor sample fragments will be treated with various combination of chemotherapy and immunotherapy drugs that are commonly used to treat patients clinically (panel of drugs will be selected based on cancer type). response to the treatment will be assessed at multiple timepoints during a 72-hour period.

    Up to 72 hours

Interventions

No interventionOTHER

Lab-based correlative study; no intervention

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Male and female patients planning to undergo surgery for removal of cancer at Mayo Clinic in Florida.

You may qualify if:

  • Ability to understand and sign informed consent
  • Planning to undergo a surgical procedure to remove cancer

You may not qualify if:

  • No tissue for research available at time of surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States

RECRUITING

Related Links

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Debabrata Mukhopadhyay, PhD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Clinical Trials Referral Office

CONTACT

855-776-0015mayocliniccancerstudies@mayo.edu

Megan Warner

CONTACT

Warner.Megan@mayo.edu

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 23, 2025

First Posted

June 3, 2025

Study Start

July 1, 2025

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 1, 2028

Last Updated

May 22, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations

US(1)