NCT05708495

Brief Summary

Aim of the study is to investigate the effect of adding posterior ilium mobilization on knee pain, knee function, anterior pelvic tilt, dynamic knee valgus, muscle strength of extensors, abductors and external rotators of hip and knee extensors in patients with patellofemoral pain syndrome.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 23, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 1, 2023

Completed
4 months until next milestone

Study Start

First participant enrolled

June 1, 2023

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2024

Completed
Last Updated

May 30, 2025

Status Verified

September 1, 2024

Enrollment Period

11 months

First QC Date

January 23, 2023

Last Update Submit

May 24, 2025

Conditions

Patellofemoral Pain Syndrome

Keywords

patellofemoral pain syndromestrengthstretchmobilizationiliuminnominate

Outcome Measures

Primary Outcomes (2)

  • Changes in pain

    Arabic Numeric pain rating scale will be used to assess pain changes during walking, hopping, squatting, stair negotiation, kneeling, or prolonged sitting. This scale measures pain severity on a scale of 0 to 10 points, with 0 representing no pain and 10 signifying the most severe pain possible.

    It will be assessed at baseline and after 4 weeks

  • Changes in knee functional disability

    The Arabic version of Anterior knee pain scale will be used to assess the knee functional disability. It is a self-administered, weighted questionnaire that analyzes 13 items, including pain and function, with a maximum score of 100 points and minimum score of 0 points. Higher scores indicate greater lower extremity function. It documents responses to six activities linked with anterior knee pain (walking, running, jumping, climbing stairs, squatting, and sitting for prolonged periods with knee bent).

    It will be assessed at baseline and after 4 weeks

Secondary Outcomes (6)

  • Changes in hip abductors strength

    It will be assessed at baseline and after 4 weeks

  • Changes in hip extensors strength

    It will be assessed at baseline and after 4 weeks

  • Changes in hip external rotators strength

    It will be assessed at baseline and after 4 weeks

  • Changes in knee extensors strength

    It will be assessed at baseline and after 4 weeks

  • Changes in dynamic knee valgus

    It will be assessed at baseline and after 4 weeks

  • +1 more secondary outcomes

Study Arms (2)

Control group

ACTIVE COMPARATOR
Other: strengthening and stretching exercises

Study group

EXPERIMENTAL
Other: posterior ilium mobilizationOther: strengthening and stretching exercises

Interventions

posterior ilium mobilizationOTHER

the therapist will mobilize the innominate on the affected side posteriorly

Study group
strengthening and stretching exercisesOTHER

the participants will receive strengthening exercises on the hip and knee joint beside that they will receive stretching exercises

Control groupStudy group

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age of the subjects between 18-35 years.
  • BMI will be ≤ 29.5
  • Anterior or retro patellar knee pain for at least 6 weeks duration.
  • Foot posture index score from +6 to +12.
  • Anterior pelvic tilt angle more than 8 degree.
  • Pain elicited at least by two of the following four tests; (i) Isometric muscle contraction with slight bent knee,(ii) palpation of the patellofemoral joint line, (iii) patellar compression against the femoral bone (iv) active resisted knee extension.
  • Pain intensity more than 3 at ANPS and provoked by at least two of the following activities: running, walking, hopping, squatting, stair negotiation, kneeling, or prolonged sitting.

You may not qualify if:

  • Meniscal or other intraarticular pathologic conditions; cruciate or collateral ligament involvement.
  • A history of traumatic patellar subluxation or dislocation.
  • Previous surgery in the knee, ankle and hip joints.
  • Knee, ankle and hip joints osteoarthritis.
  • Taking non-steroidal anti-inflammatory drugs or corticosteroids within 24 h before the test.
  • History of brain injury or vestibular disorder within the last 6 months.
  • Pregnant female.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Giza, Egypt

Location

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Lecturer Of Orthopedic Physical Therapy, Faculty Of Physical Therapy

Study Record Dates

First Submitted

January 23, 2023

First Posted

February 1, 2023

Study Start

June 1, 2023

Primary Completion

May 1, 2024

Study Completion

May 1, 2024

Last Updated

May 30, 2025

Record last verified: 2024-09

Locations

EG(1)