NCT06965595

Brief Summary

Gynecological pelvic surgeries include procedures such as myomectomy, hysterectomy, and removal of ovarian cysts performed in the pelvic region of women. In the postoperative period following these surgeries, symptoms such as pain, decreased bowel motility, gastrointestinal problems, nausea, and vomiting are commonly observed. Effective management of these symptoms is important to accelerate the recovery process and improve the quality of life of patients. This study is planned to evaluate the effectiveness of physiotherapy during the hospitalization period after gynecological abdominal surgery and to examine the effects of different approaches on postoperative symptoms. In our study, participants who undergo gynecological abdominal surgery and meet the inclusion and exclusion criteria will be divided into four groups for intervention. In addition to routine care, interventions including physiotherapy, vagal stimulation, and a combination of physiotherapy and vagal stimulation will be applied from the postoperative period until discharge. The effects of these interventions on pain, bowel function, autonomic functions, pelvic floor function, and walking will be examined.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
1mo left

Started Jun 2025

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress93%
Jun 2025Jun 2026

First Submitted

Initial submission to the registry

March 28, 2025

Completed
1 month until next milestone

First Posted

Study publicly available on registry

May 11, 2025

Completed
21 days until next milestone

Study Start

First participant enrolled

June 1, 2025

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2026

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Expected
Last Updated

August 1, 2025

Status Verified

July 1, 2025

Enrollment Period

10 months

First QC Date

March 28, 2025

Last Update Submit

July 30, 2025

Conditions

Keywords

Gynecological abdominal surgerypostoperative routine carephysiotherapy and rehabilitationvagal stimulation

Outcome Measures

Primary Outcomes (14)

  • Postoperative Pain (VAS)

    Pain will be assessed before and after each session. Visual Analog Scale (VAS) will be used for this. Minimum value is 0 and max value is 10. Ten is a higher pain. Zero means no pain.

    Day 1 and Day 2

  • Pain threshold measurement

    A digital algometer device will be used to determine the pain threshold.

    Baseline and Day 2

  • Assessment of Autonomic Functions

    The recording will be made with an ECG device.R-R waves will be examined.

    Day 1 and Day 2

  • Assessment of Autonomic Functions

    heart rate collected before and after the session.

    Day 1 and Day 2

  • Assessment of Autonomic Functions

    Blood Pressure collected before and after the session.

    Day 1 and Day 2

  • Assessment of Autonomic Functions

    respiratory rate collected before and after the session.

    Day 1 and Day 2

  • Assessment of saturation (SpO₂)

    arterial oxygen saturation (SpO₂) levels of participants will be evaluated. The unit of measurement will be the percentage of oxygen saturation.

    Day 1 and Day 2

  • Postoperative period

    The time when the first feeling of needing to pass gas time and defecation occurs will be noted.

    From enrollment to the end of treatment at 2 day

  • The walking time

    The time of first walking will be noted.

    Postoperative

  • First food intake

    The time of First food intake will be noted.

    Postoperative

  • Take a medicine

    Analgesics and other medications taken will be noted.

    Day 1 and Day 2

  • Umblikus

    Umbilicus circumference will be measured with a tape measure.

    Day 1 and Day 2

  • xiphoid - pubis distance

    The distance between the xiphoid and pubis will be measured with a tape measure. It will be noted in cm.

    day 1 and day 2

  • Postoperative period

    The time when the first feeling of needing to urinate occurs and the time when the feeling of micturition occurs will be noted.

    Postoperative

Secondary Outcomes (9)

  • DETAILED STORIES OF THE PATIENTS

    Before treatment

  • Two minutes walk

    Day 1 and Day 2

  • Pelvic Floor

    Day 1 and Day 2

  • Pelvic Floor Distress Inventory-20 (PFDI-20)

    Day1 and Day 2

  • Quality of Recovery-40

    Day 1 and Day 2

  • +4 more secondary outcomes

Study Arms (4)

Routine Care

EXPERIMENTAL

This group will be the control group. Routine care practices carried out in the hospital (vital sign monitoring, administration of analgesics, anti-inflammatory and antibiotics when necessary, and mobilization starting from the 6th hour) will be applied and the data will be recorded.

Other: Routine care

Rutin care + Physiotherapy

ACTIVE COMPARATOR

In addition to routine care practices, this group will receive physiotherapy and rehabilitation. During the postoperative period, the intervention will be applied twice a day.

Other: Routine care + Physiotherapy

Routine care + vagal stimulation

ACTIVE COMPARATOR

In addition to routine care practices, this group will receive vagal stimulation. The stimulation will be applied to the cervical region at 10 Hz, 200 μs for 20 minutes, twice a day.

Other: Routine care + Vagal stimulation

Routine care + Physiotherapy + Vagal stimulation

ACTIVE COMPARATOR

In addition to routine care practices, this group will receive physiotherapy and rehabilitation, along with vagal stimulation.

Other: Routine care + Physiotherapy + Vagal stimulation

Interventions

This group will be the control group. Routine care practices carried out in the hospital (vital sign monitoring, administration of analgesics, anti-inflammatory and antibiotics when necessary, and mobilization starting from the 6th hour) will be applied and the data will be recorded.

Routine Care

In addition to routine care practices, this group will receive physiotherapy and rehabilitation. During the postoperative period, the intervention will be applied twice a day. Posture training: Information about posture will be provided in different positions and training will be conducted. Breathing training (Diaphragmatic breathing, thoracic expansion exercises) In-bed mobilization (Lower and upper extremity exercises, foot-ankle exercises (dorsiflexion-plantar flexion / inversion-eversion), hip and knee flexion-extension exercises, cervical region joint range of motion and stretching exercises, upper extremity exercises (shoulder elevation, circumduction, elbow and wrist flexion-extension exercises), pelvic floor training and exercises) Out-of-bed mobilization (Sitting, standing, walking training after the 6th hour)

Rutin care + Physiotherapy

In addition to routine care practices, this group will receive vagal stimulation. The stimulation will be applied to the cervical region at 10 Hz, 200 μs for 20 minutes, twice a day.

Routine care + vagal stimulation

In addition to routine care practices, this group will receive physiotherapy and rehabilitation, along with vagal stimulation.

Routine care + Physiotherapy + Vagal stimulation

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Being 18 years of age or older
  • Having undergone surgery due to a gynecological condition
  • Having undergone one of the following operations: hysterectomy, hysterectomy + oophorectomy, or hysterectomy + salpingo-oophorectomy
  • Having undergone abdominal surgery

You may not qualify if:

  • Development of any complications during or after surgery
  • Presence of active malignancy
  • Presence of severe organ failure
  • Presence of uncontrolled cardiac or other systemic disorders
  • Presence of neurological or cognitive diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nuh Naci Yazgan Unıversıty

Kayseri, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Physical Therapy Modalities

Intervention Hierarchy (Ancestors)

TherapeuticsRehabilitation

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized controlled trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr.

Study Record Dates

First Submitted

March 28, 2025

First Posted

May 11, 2025

Study Start

June 1, 2025

Primary Completion

April 1, 2026

Study Completion (Estimated)

June 1, 2026

Last Updated

August 1, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations