Comparison of ACB With ACB and BiFeS Combination in Knee Arthroplasty Surgeries

NCT07233785 | Not Yet Recruiting

• 1 other identifier: 2025-09/52
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim is to compare the postoperative analgesic effects of Adductor Canal and Biceps Femoris Short Head Blocks with Adductor Canal Block in patients undergoing Knee Arthroplasty surgery

Conditions

Postoperative Pain Management; Knee Surgery; Knee Arthroplasty, Total

Keywords

postoperative pain; knee arthroplasty; biceps femoris short head; bifes; adductor canal blok; regional anesthesia

Outcome Measures

Primary Outcomes (1)

• 1. Numeric Rating Scale (NRS) Scores

  Numerical rating scale is used for pain assessment. The scores of the numerical rating scale changes between 0 to 10 points. 10 points mean "the most severe pain that the patient ever had". 0 point means "there is no pain." Higher scores mean worse outcome.

  Postoperative 24 hours

Secondary Outcomes (1)

• Total tramadol consumption

  Postoperative 24 hours

Study Arms (2)

Adductor Canal Block

ACTIVE COMPARATOR

For an adductor canal block, a high-frequency ultrasound probe will be placed on the anterior aspect of the patient's thigh, approximately at the midpoint between the inguinal crease and the medial condyle of the knee. (The depth is generally 3-5 cm). Using an in-plane technique, the needle will be advanced from lateral to medial, passing through the sartorius or vastus medialis muscle, and 20 mL of 0.25% bupivacaine will be injected around the femoral artery.

Procedure: Adductor Canal Block (ACB) Only

Combination of Adductor Canal Block and Biceps Femoris Short Head Block

ACTIVE COMPARATOR

For adductor canal block, a high-frequency ultrasound probe will be placed on the anterior aspect of the patient's thigh, approximately at the midpoint between the inguinal crease and the medial condyle of the knee. (The depth is generally 3-5 cm). Using in-plane technique, the needle passing through the sartorius or vastus medialis muscle, and 20 mL of 0.25% bupivacaine will be injected around the femoral artery. For BiFeS block, a high-frequency ultrasound probe will be placed on the distal posterior aspect of the thigh. The Biceps Femoris Short Head (BiFeS) muscle will be visualized at the distal lateral part of the femur, near the lateral supracondylar line, and the needle tip will be placed at the interface between the BiFeS and the lateral supracondylar line of the femur. 20 mL of 0.25% bupivacaine will be injected, and during the injection, it will be confirmed by ultrasound that the solution lifts the muscle and spreads along the bone surface.

Procedure: Adductor Canal Block (ACB) + Biceps Femoris Short Head Block (BiFeS)

Interventions

Adductor Canal Block (ACB) Only PROCEDURE

20 mL of 0.25% bupivacaine

Adductor Canal Block

Adductor Canal Block (ACB) + Biceps Femoris Short Head Block (BiFeS) PROCEDURE

20 mL of 0.25% bupivacaine

Combination of Adductor Canal Block and Biceps Femoris Short Head Block

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patients over 18 years of age who underwent percutaneous nephrolithotomy under general anesthesia and were I-II-III according to the American Society of Anesthesiologists (ASA) risk classification were included in the study.

You may not qualify if:

• patients who did not give consent,
• patients with coagulopathy,
• patients with signs of infection at the block application site,
• patients using anticoagulants,
• patients with known allergies to any of the study drugs,
• patients with unstable hemodynamics,
• patients who could not cooperate during postoperative pain assessment
• patients who wanted to withdraw from the study,
• patients with alcohol and drug addiction,
• patients with musculoskeletal abnormalitie

Sponsors & Collaborators

• Cumhuriyet University: lead

Study Sites (1)

Sivas Cumhuriyet University School of Medicine, Anesthesiology and Reanimation

Sivas, Sivas, 58140, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative

Interventions

Single Person

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Marital Status; Family Characteristics; Demography; Population Characteristics; Socioeconomic Factors

Study Officials

• OĞUZ GÜNDOĞDU

  Sivas Cumhuriyet University School of Medicine, Anesthesiology and Reanimation

  PRINCIPAL INVESTIGATOR

• BUĞRA KARATAŞ

  Sivas Cumhuriyet University School of Medicine, Anesthesiology and Reanimation

  STUDY CHAIR

Central Study Contacts

OĞUZ GÜNDOĞDU

CONTACT

+905545945469; droguzgundogdu@gmail.com

BUĞRA KARATAŞ

CONTACT

+905412453634; bugrabgr60@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: November 14, 2025
• First Posted: November 18, 2025
• Study Start: November 20, 2025
• Primary Completion (Estimated): October 25, 2026
• Study Completion (Estimated): November 25, 2026
• Last Updated: November 25, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)