Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Plus Biceps Femoris Short Head Block in Patients Undergoing Knee Arthroscopy

NCT07242339 | Recruiting

• 1 other identifier: Bifes knee
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective, randomized, controlled, and multicenter clinical study aims to compare the postoperative analgesic efficacy of two regional anesthesia techniques commonly used in knee arthroscopy: adductor canal block (ACB) and combined adductor canal block plus biceps femoris short head (ACB+BiFeS) block. The study will evaluate postoperative pain control, opioid consumption, adverse effects, hospital stay, and patient satisfaction. Findings will help determine the most effective and safe method for postoperative analgesia in knee arthroscopy patients.

Conditions

Postoperative Pain Management

Keywords

regional anesthesia

Outcome Measures

Primary Outcomes (1)

• Total Opioid Consumption (Tramadol, mg)

  The total dose of tramadol administered via intravenous patient-controlled analgesia (PCA) device within the first 24 hours postoperatively will be recorded in milligrams.

  24 hours

Secondary Outcomes (6)

• Postoperative Pain with Movement and at rest (NRS)

  At 0, 6, 12, and 24 hours after surgery

• Rescue Analgesia Requirement

  Within the first 24 hours postoperatively

• Incidence of Nausea and Vomiting

  Within the first 24 hours postoperatively

• Quality of Recovery (QOR-15 score)

  At 24 hours after surgery

• Dermatomal Spread of Block

  2nd hour postoperatively

Study Arms (2)

Adductor Canal Block (ACB)

ACTIVE COMPARATOR

Participants will undergo ultrasound-guided adductor canal block at the end of surgery under spinal anesthesia.

Procedure: Adductor Canal Block (ACB) Only

Adductor Canal Block + Biceps Femoris Short Head Block (ACB+BiFeS)

ACTIVE COMPARATOR

Participants will undergo both adductor canal block and biceps femoris short head block at the end of surgery under spinal anesthesia.

Procedure: biceps femoris short head block + Adductor Canal Block (ACB)

Interventions

Adductor Canal Block (ACB) Only PROCEDURE

Ultrasound-guided injection of 10 mL 0.25% bupivacaine into the adductor canal targeting the femoral artery region, providing motor-sparing analgesia to the medial/anterior knee.

Adductor Canal Block (ACB)

biceps femoris short head block + Adductor Canal Block (ACB) PROCEDURE

Combination of adductor canal block (10 mL 0.25% bupivacaine) and biceps femoris short head block with 25 mL 0.25% bupivacaine, deposited at the interfascial plane between BiFeS muscle and lateral femoral cortex to extend analgesia to the posterolateral knee.

Adductor Canal Block + Biceps Femoris Short Head Block (ACB+BiFeS)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18 years
• ASA physical status I-III
• Scheduled for elective knee arthroscopy under spinal anesthesia
• Ability to provide written informed consent

You may not qualify if:

• Coagulopathy or bleeding diathesis
• Current use of anticoagulant therapy
• Known allergy or contraindication to local anesthetics used in the study
• History of diabetes mellitus with neuropathy or other neuropathic disorders
• Contraindications to regional anesthesia techniques
• Refusal to participate

Sponsors & Collaborators

• Kanuni Sultan Suleyman Training and Research Hospital: lead

Study Sites (1)

Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital

Istanbul, küçükçekmece, 34303, Turkey (Türkiye)

RECRUITING

MeSH Terms

Interventions

Single Person

Intervention Hierarchy (Ancestors)

Marital Status; Family Characteristics; Demography; Population Characteristics; Socioeconomic Factors

Study Officials

• Engin ihsan Turan, Specialist

  Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Engin ihsan Turan, principal investigator

CONTACT

+905382431114; enginihsan@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Participants will be blinded to group allocation. Outcome assessors recording pain scores, opioid consumption, and side effects will be blinded to the intervention. The anesthesiologists performing the blocks cannot be blinded due to the nature of the procedures.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Model Details: Participants will be randomized in a 1:1 ratio to receive either an adductor canal block (ACB) or a combined adductor canal plus biceps femoris short head (ACB+BiFeS) block. Both interventions will be performed under ultrasound guidance at the end of surgery.

Study Record Dates

• First Submitted: November 17, 2025
• First Posted: November 21, 2025
• Study Start: November 20, 2025
• Primary Completion: March 10, 2026
• Study Completion: March 30, 2026
• Last Updated: January 20, 2026

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)