Clinical Trial to Evaluate the Efficacy of Skin Products to Improve Skin Quality and Health

NCT06853899 | Completed

• 1 other identifier: 20455
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical trial evaluates the efficacy of three skincare products-Truology A2 (0.2% Retinaldehyde Serum), Truology C-Boost, and Truology Barrier Restore-in improving skin quality and health. The study will assess improvements in skin firmness, evenness, brightness, hydration, fine lines/wrinkles, redness, and skin stress/irritation.

Conditions

Skin Hydration; Skin Aging

Keywords

Skin Quality; Facial Skin Health

Outcome Measures

Primary Outcomes (1)

• Improvement in self-reported skin health symptoms (measured via questionnaires)

  Baseline, Day 1, Week 2, Week 4, Week 6

Secondary Outcomes (1)

• Changes in overall facial skin quality and health (measured via expert skin grading)

  Baseline and Week 6

Study Arms (1)

Truology Skincare Routine

EXPERIMENTAL

A single-arm study in which all participants will use the Truology Skincare Routine for 6 weeks.

Dietary Supplement: Truology A2; Dietary Supplement: Truology C-Boost; Dietary Supplement: Truology Barrier Restore

Interventions

Truology A2 DIETARY_SUPPLEMENT

Truology A2 (0.2% Retinaldehyde Serum) - Applied once daily at night after cleansing.

Truology Skincare Routine

Truology C-Boost DIETARY_SUPPLEMENT

Truology C-Boost - Applied twice daily (morning \& night).

Truology Skincare Routine

Truology Barrier Restore DIETARY_SUPPLEMENT

Applied twice daily (morning \& night) as the final skincare step.

Truology Skincare Routine

Eligibility Criteria

• Age: 35 Years - 55 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Be female-at-birth
• Be aged 35-55
• Anyone currently experiencing issues with skin health, including: Poor skin texture, Skin discoloration, Appearance of fine lines and wrinkles Dull skin, Poor skin firmness, Dry skin, Skin redness, Irritated and stressed skin
• Willing to use the test products as follows: Truology A2 - Once a day at night. Use 1 pump for the whole face. Use first after cleansing the skin on dry skin. C-Boost - Twice a day (AM \& PM). In the morning, first use one pump for the full face after cleansing the skin. At night, use the A2 first, then C-Boost. Barrier Restore - Twice a day (AM \& PM). Use one pump for the full face. Use it after C-Boost for the final step in the skincare routine, and complete questionnaires and take photos
• Have been using the same skincare routine for at least one month prior to the study, i.e., cleanser, toner, and make-up remover
• Willing to maintain the same skincare routine and products throughout the 6-week trial, e.g., moisturizer, cleanser, or SPF
• Have been consistently taking medications, oral supplements, or herbal remedies targeted at skin health and appearance for at least 3 months prior to the study and willing to maintain this routine for the duration of the study
• Agree to avoid using any other products or new forms of regular medication or supplements that target skin health and appearance
• Anyone who is generally healthy - does not live with any uncontrolled chronic disease
• Anyone who is currently using or has used the past, exfoliating acids (AHAs/BHA) or retinoids in (i.e., salicylic acid, glycolic acid, mandelic acid, or lactic acid).
• Anyone willing to stop using exfoliating acids or retinoids for the duration of the study
• Anyone in good general health
• Anyone who resides in the United States

You may not qualify if:

• Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders
• Anyone currently using a prescription skin treatment
• Anyone with known severe allergic reactions
• Anyone unwilling to avoid excessive sun exposure
• Any women who are pregnant, breastfeeding, or attempting to conceive
• Anyone unwilling to follow the study protocol
• Anyone who identifies as having sensitive skin
• Anyone who has undergone any facial surgeries or invasive skin treatments in the last 6 months
• Anyone who is planning to undergo any facial treatments during the study period, including botox, dermal filler, or chemical peels
• Anyone who has not stopped using hormonal birth control within the past month
• Anyone with any chronic skin conditions on the face (e.g., eczema or psoriasis)
• Anyone with a history of skin cancer or pre-cancerous skin lesions on the face
• Anyone currently testing, or plans to in the next 6 weeks, a product for another research study
• Anyone with a history of substance abuse
• Anyone who is currently, or has been for the past 3 months, a smoker

Sponsors & Collaborators

• Truology: lead
• Citruslabs: collaborator

Study Sites (1)

Citruslabs

Las Vegas, Nevada, 89118, United States

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 25, 2025
• First Posted: March 3, 2025
• Study Start: October 21, 2024
• Primary Completion: January 10, 2025
• Study Completion: January 10, 2025
• Last Updated: March 3, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)