NCT06836193

Brief Summary

The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds in individuals with chronic pain.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
152

participants targeted

Target at P75+ for not_applicable

Timeline
20mo left

Started Jan 2026

Typical duration for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress17%
Jan 2026Dec 2027

First Submitted

Initial submission to the registry

February 12, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 20, 2025

Completed
11 months until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2027

Expected
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Last Updated

February 20, 2025

Status Verified

February 1, 2025

Enrollment Period

1.4 years

First QC Date

February 12, 2025

Last Update Submit

February 17, 2025

Conditions

PRESSURE PAIN THRESHOLD

Keywords

Pressure Pain ThresholdPainEmotion

Outcome Measures

Primary Outcomes (1)

  • Pressure pain thresholds will be measured in kPa

    Pressure pain thresholds will be measured in kPa using a handheld algometer (Somedic AB).

    The measurement takes place at the intervention session. First a baseline measurement is conducted, then comes the intervention and then the intervention measurement takes place.

Study Arms (4)

Negative emotional condition

EXPERIMENTAL

The participant will watch a short video-clip with negative emotional content.

Other: Emotional intervention

Positive emotional condition

EXPERIMENTAL

The participant will watch a short video-clip with positive emotional content.

Other: Emotional intervention

Neutral emotional condition

SHAM COMPARATOR

The participant will watch a short video-clip with neutral emotional content.

Other: Emotional intervention

No emotional condition

SHAM COMPARATOR

The participant will wait for 2.30 minutes without any instructions about how to engage their thoughts.

Other: Emotional intervention

Interventions

Emotional interventionOTHER

Negative emotional intervention

Negative emotional conditionNeutral emotional condition

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Above 18 years of age
  • Fluent in Swedish

You may not qualify if:

  • Known neurological disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Helena Gunnarsson, Dr

CONTACT

+46708432509helena.gunnarsson@lnu.se

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

February 12, 2025

First Posted

February 20, 2025

Study Start

January 1, 2026

Primary Completion (Estimated)

June 1, 2027

Study Completion (Estimated)

December 31, 2027

Last Updated

February 20, 2025

Record last verified: 2025-02