Effect of Early Mobilization Exercises After Coronary Artery Bypass Graft

NCT06801314 | Completed DMC

• 1 other identifier: P.T.REC/012/005234
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

purpose: This study aims to assess the effects of early mobilization exercises guided by wearable technology on functional capacity after coronary artery bypass graft Methods: Patients will be randomly assigned into three groups: Group A will receive usual care, Group B will receive usual care in addition to aerobic exercise, and Group C will receive usual care in addition to resistance exercise. both the aerobic exercise group and the resistance exercise group will be guided by wearable artificial intelligence ECG monitors for real-time support and guidance, and they will stop exercise when any adverse events occur. Exercises will be started early from post operative CABG until patients discharge and measurements will be taken at baseline and before discharge

Conditions

Coronary Artery Bypass Graft CABG

Keywords

CABG

Outcome Measures

Primary Outcomes (1)

• Functional capacity

  Functional capacity: It will be assessed by 6MWT test. According to the American Thoracic Society,

  at baseline before intervention and 1 week after intervention

Secondary Outcomes (7)

• Heart rate variability

  at baseline before intervention and 1 week after intervention

• - Muscle strength

  at baseline before intervention and 1 week after intervention

• - Kinesiophobia

  at baseline before intervention and 1 week after intervention

• - Functional independence

  at baseline before intervention and 1 week after intervention

• - Length of hospital stay

  after 1 week of intervention

Study Arms (3)

control group (A) usual care

ACTIVE COMPARATOR

patients in this group will receive usual care including moibilizations and breathing exercise

study group (B)aerobic exercise (using cycle ergometer) in addition to usual care

EXPERIMENTAL

Patients in this group will be received usual care and cycle ergometer aerobic exercise

Other: aerobic exercise using cycle ergometer in addition to usual care

study group(C)resisted exercise group (using weights and dumbbells) in addition to usual care

EXPERIMENTAL

Patients in this group will be received usual care and resisted exercise

Other: resisted exercise using weights and dumbbells in addition to usual care

Interventions

aerobic exercise using cycle ergometer in addition to usual care OTHER

aerobic exercise group):Patients in this group will be received usual care and cycle ergometer aerobic exercise Mood of exercise: continuous aerobic exercise * Modality of exercise: cycle ergometer * Intensity of exercise: low to moderate intensity and HR (calculated as recommended by the American College of Sports Medicine (ACSM) and tolerated up to 20-30 bpm above the resting HR), BP, SpO2 and rate of perceived exertion through the Borg Scale (10-13) will be monitor during cycling * Duration: 15-20 min including 5 min warm up and 5 min cool down and working phase from 5-10 min * Frequency: daily until discharge aerobic exercise group guided by wearable artificial intelligence ECG monitor to real-time support, guide and stop exercise when there is any adverse events will occur.

study group (B)aerobic exercise (using cycle ergometer) in addition to usual care

resisted exercise using weights and dumbbells in addition to usual care OTHER

resisted exercise group): Patients in this group will be received usual care and resisted exercise * Mode: resisted exercise * Modality: dumbbells or sand bags tied around main groups of muscles for upper and lower limbs Intensity of exercise: the load that the patient can lift for 10-12 repetition at RPE of 10-13 and 1-2 sets resisted exercise group guided by wearable artificial intelligence ECG monitor to real-time support, guided and stop exercise when there is any adverse events will occur.

study group(C)resisted exercise group (using weights and dumbbells) in addition to usual care

usual care using mobilization and breathing exercise OTHER

mobilization and breathing exercise

Eligibility Criteria

• Age: 45 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• post -operative clinically stable patients with hemodynamic stability through measurement of respiratory rate( \>8\<30) breaths/min , Heart rate (\>40\<130) beats /min , Spo2\>90% 2-both lower limbs will be physically functional 3-CABG surgery 4-Their age will be ranged from 45-65 years old

You may not qualify if:

• Respiratory insufficiency after surgery manifesting hypoxemia with partial pressure of oxygen in arterial blood \<60 mmHg
• Cardiogenic shock
• acute renal failure
• contra-indicated to submaximal exercise test
• cardiac arrhythmia
• locomotor/neurological limitation to ambulation
• physiological compensatory tachycardia in case of (anemia, high tempreture and infection)
• high blood pressure at rest (systolic blood pressure \>160mmHg or diastolic blood pressure \>100 mmHg -

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of physical therapy, Cairo university

Giza, Egypt, 11432, Egypt

Location

MeSH Terms

Interventions

Breathing Exercises

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Ahmad Mahdy Ahmad, A.professor

  Cairo University

  STUDY DIRECTOR

• NESREEN G EL_NAHAS, professor

  Cairo University

  STUDY CHAIR

• Sara Ali AWAD ALLAH, Assistant professor

  Cairo University

  PRINCIPAL INVESTIGATOR

• Alaa Eldin Abdelaty Bahy, consultant

  Cairo University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: double blinded(participant ,, investigator )
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer

Model Details: patients will be randomly assigned into three groups, group A will receive usual care , group B will receive usual care in addition to aerobic exercise and group C will receive usual care in addition to resisted exercise

Study Record Dates

• First Submitted: January 16, 2025
• First Posted: January 30, 2025
• Study Start: February 1, 2025
• Primary Completion: August 30, 2025
• Study Completion: September 30, 2025
• Last Updated: November 25, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)