Investigation of the Effect of Prehabilitation Practice on Patient Outcomes in Frail Patients Planned for Elective Coronary Artery Bypass Graft

NCT07138534 | Not Yet Recruiting

• 1 other identifier: 20250715
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

The basic concept of prehabilitation is to increase the functional capacity of the individual to withstand an expected injury. It embodies the idea of being proactive against the common reactive approach of rehabilitation. While the initial prehabilitation model was limited to physical training, it has now evolved into a multimodal entity that includes nutritional optimisation, psychosocial preparation and smoking cessation in addition to exercise programmes. In the last decade, there has been an increasing effort to coincide prehabilitation with surgery, as surgery is rightly perceived as a stressor for human structural and physiological functions.

Conditions

Coronary Artery Bypass Graft (CABG)

Keywords

frail patients; coronary artery bypass

Outcome Measures

Primary Outcomes (4)

• patients' activities of daily living

  Patients' daily living activities will be assessed according to the Katz Daily Living Activities Scale. Those with high scores will be shown to have better daily living activities. scale name: Katz activities of daily living. 6 is the highest score and 0 is the lowest. A score of 6 means completely independent.

  It will be measured one month after the surgery. The date may vary depending on the patient.

• functional capacity

  Patients' functional capacities will be assessed using the Duke Activity Scale. Those with high scores will be confirmed to have better physical and functional capacities. scale name: Duke Activity Status Index. The lowest score is 0 and the highest score is 58.2. A score of 58.2 indicates the highest functional capacity.

  It will be evaluated one month after surgery. The date may vary depending on the patient.

• Nutritional Status

  Patients' nutrition will be assessed using a mini nutritional test. Those who score high will be assumed to be in good nutritional condition. scale name: Mini nutritional test. The highest score is 14 and the lowest is 0. The highest score indicates the absence of malnutrition.

  It will be evaluated one month after surgery. The date may vary depending on the patient.

• Post-operative recovery status

  The patient's physical, psychological, bowel activity and general condition will be assessed using a post-operative recovery index. Those with high scores will be considered to have recovered better. The scale name is the postoperative recovery index. The index consists of 5 sub-dimensions and 25 items. The sub-dimensions are psychological symptoms, physical activities, and general symptoms. The ASII total and sub-dimension scores are bowel symptoms and desire-urge symptoms. When determining the subscale score, the scores of the relevant items are summed and the arithmetic mean is calculated. For the total score, all items are summed and the arithmetic mean is calculated. High scores on the index indicate greater difficulty in post-operative recovery, while low scores indicate that post-operative recovery is easier. The ASII is a reliable and valid tool for assessing

  It will be measured one month after the surgery.

Study Arms (2)

routine procedure

NO INTERVENTION

control

prehabilitation

EXPERIMENTAL

In addition to exercise programmes, it includes nutritional optimisation, psychosocial preparation and smoking cessation.

Behavioral: prehabilitation

Interventions

prehabilitation BEHAVIORAL

In addition to exercise programmes, it includes nutritional optimisation, psychosocial preparation and smoking cessation.

prehabilitation

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• frail patient

You may not qualify if:

• frail patient

Sponsors & Collaborators

• Bahçeşehir University: lead

Related Publications (1)

• Steinmetz C, Bjarnason-Wehrens B, Walther T, Schaffland TF, Walther C. Efficacy of Prehabilitation Before Cardiac Surgery: A Systematic Review and Meta-analysis. Am J Phys Med Rehabil. 2023 Apr 1;102(4):323-330. doi: 10.1097/PHM.0000000000002097. Epub 2022 Sep 23.

  PMID: 36149383 BACKGROUND

Related Links

• This page is related to Eras cardiac. It is a recommendation from the Eras prehabilitation guidelines. This study was deemed appropriate due to the very low level of evidence.

MeSH Terms

Interventions

Preoperative Exercise

Intervention Hierarchy (Ancestors)

Perioperative Care; Patient Care; Therapeutics; Surgical Procedures, Operative; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Health Services; Health Care Facilities Workforce and Services

Study Officials

• FATMA ETİ ASLAN, Proffesor

  Bahcesehir Universty

  STUDY DIRECTOR

Central Study Contacts

Gamze Ataman Yıldız, Phd student

CONTACT

+905427751780; gamzeataman39@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Surgical Nurse

Study Record Dates

• First Submitted: August 5, 2025
• First Posted: August 24, 2025
• Study Start: September 1, 2025
• Primary Completion: December 30, 2025
• Study Completion: December 30, 2025
• Last Updated: August 24, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share