NCT06796036

Brief Summary

The aim of the project is to investigate whether the integration of artificial intelligence (AI) support, specifically through the GPT-4 model, enhances the decision-making processes of military medical first responders within the framework of Tactical Combat Casualty Care (TCCC). The study focuses on AI's ability to assist in ventilator settings for injured individuals in combat scenarios, emphasizing improved accuracy and decision-making speed. The project tests the hypothesis that the use of AI can positively impact outcomes without compromising the autonomy of first responders. The results have the potential to optimize patient care in challenging conditions and contribute to the advancement of combat medicine.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 22, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 28, 2025

Completed
5 days until next milestone

Study Start

First participant enrolled

February 2, 2025

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2025

Completed
Last Updated

May 13, 2025

Status Verified

May 1, 2025

Enrollment Period

2 months

First QC Date

January 22, 2025

Last Update Submit

May 12, 2025

Conditions

Keywords

artificial intelligencecombat medicinedecision-makingmechanical ventilation

Outcome Measures

Primary Outcomes (1)

  • Accuracy of ventilator settings

    Accuracy of ventilator settings as categorized into "excellent," "acceptable," or "failing" based on predefined TCCC standards. Excellent means 2 points, acceptable 1 point and failing 0 point.

    1 hour

Other Outcomes (1)

  • Perception of artificial intelligence's utility

    1 hour

Study Arms (1)

Combat Medic Decision-Making with and without AI Assistance

EXPERIMENTAL

All participants will complete 10 Tactical Combat Casualty Care scenarios: 5 with AI assistance using GPT-4 for ventilator management and 5 without AI assistance. The crossover design ensures each participant experiences both conditions.

Other: Combat Medic Decision-Making with and without artificial intelligence assistance

Interventions

Participants will complete 10 simulated Tactical Combat Casualty Care (TCCC) scenarios, with 5 scenarios conducted using AI assistance (GPT-4) and 5 without AI. In AI-assisted scenarios, participants will use GPT-4 to query and optimize ventilator settings based on patient data, while non-AI scenarios rely solely on their clinical judgment.

Combat Medic Decision-Making with and without AI Assistance

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Combat medics actively serving in the Czech Armed Forces
  • Completion of standardized Tactical Combat Casualty Care training modules and e-learning on ventilator settings and blood gas interpretation
  • Successful passing of pre-tests to ensure a uniform baseline knowledge level.
  • Willingness to participate and provide informed consent.
  • Availability to complete the full study protocol, including 10 simulated scenarios.

You may not qualify if:

  • Failure to pass the pre-tests or complete TCCC and ventilator management training
  • Prior advanced training or professional certification in critical care or mechanical ventilation that could bias results
  • Refusal to provide informed consent or inability to commit to the study schedule

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Military University Hospital Prague

Prague, 16209, Czechia

Location

Related Publications (2)

  • Nemeth C, Amos-Binks A, Rule G, Laufersweiler D, Keeney N, Flint I, Pinevich Y, Herasevich V. TCCC Decision Support With Machine Learning Prediction of Hemorrhage Risk, Shock Probability. Mil Med. 2023 Nov 8;188(Suppl 6):659-665. doi: 10.1093/milmed/usad298.

  • Preiksaitis C, Ashenburg N, Bunney G, Chu A, Kabeer R, Riley F, Ribeira R, Rose C. The Role of Large Language Models in Transforming Emergency Medicine: Scoping Review. JMIR Med Inform. 2024 May 10;12:e53787. doi: 10.2196/53787.

Study Officials

  • Michal Soták, M.D., Ph.D.

    Charles University, Czech Republic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: Crossover assignment (each participant acts as their own control in scenarios with and without artificial intelligence)
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 22, 2025

First Posted

January 28, 2025

Study Start

February 2, 2025

Primary Completion

March 31, 2025

Study Completion

April 30, 2025

Last Updated

May 13, 2025

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared due to concerns regarding participant confidentiality, data privacy, and the sensitive nature of the study involving military personnel. Aggregate data and study findings will be shared through peer-reviewed publications and presentations.

Locations