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6989 clinical trials

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Clinical Trials (6989)

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NCT07204938Phase 31 site

A Long-Term Study of Navenibart in Participants With Hereditary Angioedema

Enrolling By Invitation
NCT07215702Phase 24 sites

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

Recruiting
NCT06169397Phase 21 site

An Open-label Extension Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

Enrolling By Invitation
NCT05144256Phase 31 site

A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period

Active Not Recruiting
NCT04557462Phase 31 site

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

Active Not Recruiting
NCT05458297Phase 23 sites

A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

Active Not Recruiting

Mixed Reality in MitraClip Implantation: Preliminary Case Series

Completed
NCT07059845Phase 24 sites

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

Recruiting
NCT06806293Phase 310 sites

Study of Oral Atogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Active Not Recruiting
NCT06616194Phase 35 sites

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Active Not Recruiting
NCT05920356Phase 35 sites

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

Recruiting
NCT05735483Phase 32 sites

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Enrolling By Invitation
NCT04988295Phase 33 sites

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

Active Not Recruiting

Pyruvate Kinase Deficiency Global Longitudinal Registry

Active Not Recruiting
NCT07517263Phase 334 sites

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

Recruiting
NCT07067463Phase 31 site

A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

Recruiting
NCT05490446Phase 21 site

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Active Not Recruiting
NCT06170788Phase 34 sites

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

Recruiting
NCT06034743Phase 37 sites

A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

Completed
NCT06252649Phase 36 sites

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Recruiting