Rutgers University Study of the Genetics of Breast Cancer.
RUGCC-BC
The Rutgers University Genetics Coordinating Center Breast Cancer Study
1 other identifier
observational
25,000
1 country
1
Brief Summary
The goal of this observational study is to learn more about how genes impact the risk of breast cancer. Anyone 18 or older living in the US is eligible, and a diagnosis of cancer is NOT required. Study participation is online, and it takes about 20 minutes to complete health surveys and request a saliva collection kit sent through US mail. In return, study participants may opt to receive information about their genetic ancestry at no cost.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2024
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 15, 2024
CompletedFirst Submitted
Initial submission to the registry
January 8, 2025
CompletedFirst Posted
Study publicly available on registry
January 14, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 15, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
April 30, 2027
ExpectedOctober 27, 2025
October 1, 2025
2 years
January 8, 2025
October 23, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Genetic risk variants associated with breast cancer
Genetic factors will be measured through whole exome sequencing along with genotyping of common variants, and then correlated with breast cancer and breast cancer subtype.
2 years
Study Arms (2)
Breast Cancer Cases
Study participants who have been diagnosed with any form of breast cancer, either currently or in the past.
Breast Cancer Controls
Study participants who have never had a diagnosis of breast cancer.
Interventions
Saliva sample is sent via prepaid US Mail for DNA extraction
Health surveys are filled out online in the study portal.
Eligibility Criteria
The study population consists of anyone at least 18 years old who lives in the United States, including both individuals who have or had breast cancer and those who have not. Participants include males, females, non-binary, and all race-ethnic groups.
You may qualify if:
- age 18 years or older
- currently living in the United States
- able to understand and follow written instructions in English
- have access to the internet and a computer, laptop, tablet or smart phone
- willing to provide written informed consent for participation
- willing to provide DNA via a saliva sample using a collection kit mailed to the study participant's home
- willing to complete a survey with questions about health related to the study of breast cancer.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Rutgers University
Piscataway, New Jersey, 08854, United States
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Tara Matise, Ph.D.
Rutgers, The State University of New Jersey
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Distinguished Professor
Study Record Dates
First Submitted
January 8, 2025
First Posted
January 14, 2025
Study Start
April 15, 2024
Primary Completion
April 15, 2026
Study Completion (Estimated)
April 30, 2027
Last Updated
October 27, 2025
Record last verified: 2025-10
Data Sharing
- IPD Sharing
- Will not share